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yin198716

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1 Here we show that chronic DLL4 blockade causes pathological activation of endothelial cells, disrupts normal organ homeostasis and induces vascular tumours, raising important safety concerns.

2  These findings have generated hope that targeting the DLL4 pathway may provide a new strategy for cancer therapy, and DLL4-targeted agents have recently entered the clinic.
Oncology
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yin198716

新虫 (正式写手)

引用回帖:
2脗楼: Originally posted by nwsuafliu at 2013-01-16 21:57:49
1 Here we show that chronic DLL4 blockade causes pathological activation of endothelial cells, disrupts normal organ homeostasis and induces vascular tumours, raising important safety concerns.
脮芒脌茂 ...

chronic 脛茫脭玫脙麓脙禄脫脨路颅鲁枚脌麓
Oncology
3楼2013-01-17 13:48:27
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nwsuafliu

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220chengeng: 金币+1, 感谢应助 2013-01-16 22:06:00
yin198716: 金币+5, 翻译EPI+1 2013-01-17 13:51:56
1 Here we show that chronic DLL4 blockade causes pathological activation of endothelial cells, disrupts normal organ homeostasis and induces vascular tumours, raising important safety concerns.
这里,我们的研究表明DLL4阻断会引起内皮细胞的病理性激活,破坏正常的器官平衡,诱发血管肿瘤,并产生重要安全问题。

2  These findings have generated hope that targeting the DLL4 pathway may provide a new strategy for cancer therapy, and DLL4-targeted agents have recently entered the clinic.
这些发现带来了希望,靶向DLL4通路可能为癌症治疗提供新策略,而DLL4靶向药物最近已经进入临床。
知识改变命运
2楼2013-01-16 21:57:49
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yin198716

新虫 (正式写手)

引用回帖:
2脗楼: Originally posted by nwsuafliu at 2013-01-16 21:57:49
1 Here we show that chronic DLL4 blockade causes pathological activation of endothelial cells, disrupts normal organ homeostasis and induces vascular tumours, raising important safety concerns.
脮芒脌茂 ...

entered the clinic脳卯陆眉脪脩戮颅陆酶脠毛脕脵麓虏隆陋隆陋赂脨戮玫脰碌碌脙脡脤脠露拢卢虏禄鹿媒赂脨脨禄脛茫拢卢脛茫卤脧戮鹿虏禄脢脟脪陆脩搂脳篓脪碌碌脛拢卢路脟鲁拢赂脨脨禄拢隆
Oncology
4楼2013-01-17 13:52:59
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