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yin198716新虫 (正式写手)
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1 In one study, the hepatic vascular alterations observed in the Dll4 loss of function mice could be prevented by concomitant treatment with the EphrinB2 signaling inhibitors EphB4-Alb. Interestingly, the simultaneous blockade of these signaling pathways displayed additive inhibitory effects on pancreatic tumor growth and perfusion . 2This raises the intriguing possibility that the induction of vascular changes in some organs can be manipulated by combination anti-angiogenesis therapy, while at the same time additive anti-tumor effects are achieved. |
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yin198716: 金币+5, 翻译EPI+1 2013-01-11 10:56:39
yin198716: 金币+5, 翻译EPI+1 2013-01-11 10:56:39
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1 In one study, the hepatic vascular alterations observed in the Dll4 loss of function mice could be prevented by concomitant treatment with the EphrinB2 signaling inhibitors EphB4-Alb. Interestingly, the simultaneous blockade of these signaling pathways displayed additive inhibitory effects on pancreatic tumor growth and perfusion . 一项研究中，在DII4功能丧失小鼠中观察到的肝血管改变，可以被EphrinB2信号抑制剂EphB4-Alb的同步治疗阻止。有趣的是，这些信号通路的同时阻断对胰腺肿瘤生长和灌注有叠加抑制效应。 2This raises the intriguing possibility that the induction of vascular changes in some organs can be manipulated by combination anti-angiogenesis therapy, while at the same time additive anti-tumor effects are achieved. 这就产生一个诱人的可能性，某些器官中血管变化的诱导可以通过联合抗血管生长治疗予以调控，与此同时叠加抗肿瘤效应也得以实现。 |
2楼2013-01-11 09:18:55