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1 EphrinB2 has been identified as key downstream target gene of Dll4-Notch in cultured endothelial cells and during endothelial specification towards the arterial fate in mouse and zebrafish . 2 More recently,EphrinB2 regulation of VEGFR2 endocytosis and signaling in endothelial tip cells upstream of Dll4-Notch was reported. |
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yin198716: ½ð±Ò+5, ·ÒëEPI+1 2013-01-10 23:55:53
yin198716: ½ð±Ò+5, ·ÒëEPI+1 2013-01-10 23:55:53
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1 EphrinB2 has been identified as key downstream target gene of Dll4-Notch in cultured endothelial cells and during endothelial specification towards the arterial fate in mouse and zebrafish . ÔÚСÊóºÍ°ßÂíÓãÉÏ£¬EphrinB2ÔÚÅàÑøµÄÄÚÆ¤Ï¸¼°ÃæÏò¶¯Âö»¯ÃüÔ˵ÄÄÚÆ¤ÌØ»¯Öб»¼ø¶¨ÎªDll4-NotchµÄÒ»¸ö¹Ø¼üÏÂÓΰлùÒò¡£ 2 More recently,EphrinB2 regulation of VEGFR2 endocytosis and signaling in endothelial tip cells upstream of Dll4-Notch was reported. ×î½ü±¨µÀ£¬EphrinB2 ¶ÔVEGFR2ÄÚÍÌ×÷ÓúÍÄÚÆ¤¼â¶Ëϸ°ûÖÐDll4-Notchͨ·ÉÏÓεÄÐźŴ«µÝ¾ßÓе÷½Ú×÷Óᣠ|

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