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1 For example, loss of endothelial β1 integrin results in the loss of Par3 expression and the mislocalization of cell adhesion proteins Claudin-5, PECAM-1, VE-cadherin and CD99 specifically in arteries. 2 The activation of β1 integrin by Dll4-Notch1 in a CSL-independent manner suggests a possible link between Notch signaling and endothelial cell polarity. |
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