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1 Tumor vessel obstruction by intraluminal endothelial cells was recently reported in response to γ-secretase inhibitor treatment in both an orthotopic renal cell carcinoma and a VEGF-driven rabbit h ind limb angiogenesis model. 2 In contrast, however, a recent study demonstrated reduced microvascular occlusion and the modulation of vasoconstriction following inhibition of Dll4-Notch signaling during post-angiogenic remodeling in retinal angiogenesis. [ Last edited by yin198716 on 2013-1-8 at 16:29 ] |
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李氏氏
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220chengeng: 金币+1, 感谢应助 2013-01-09 14:42:34
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220chengeng: 金币+1, 感谢应助 2013-01-09 14:42:34
sltmac: 金币+5, 翻译EPI+1 2013-03-06 12:03:13
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1 Tumor vessel obstruction by intraluminal endothelial cells was recently reported in response to γ-secretase inhibitor treatment in both an orthotopic renal cell carcinoma and a VEGF-driven rabbit H ind limb angiogenesis model. 2 In contrast, however, a recent study demonstrated reduced microvascular occlusion and the modulation of vasoconstriction following inhibition of Dll4-Notch signaling during post-angiogenic remodeling in retinal angiogenesis. 1 最近有报道管腔内的内皮细胞阻塞肿瘤血管回应了γ-分泌酶抑制剂在原位肾细胞癌和血管内皮生长因子驱动的肢体血管新生模型中的治疗方法。 2然而，与此相反，最近的一项研究表明在后血管重塑视网膜血管生成过程中减少的微血管阻塞和血管收缩调制伴对于Dll4-Notch信号有抑制作用。 |
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