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yunyun89623

金虫 (小有名气)

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虫号: 1894235
注册: 2012-07-15
性别: MM
专业: 药剂学

[求助] 请帮忙翻译几句话是关于反相微乳的~~~~~~~~~谢谢啦

The relevance from this work stems from the fact that the proposed pMDI（定量吸入气雾剂） formulations may find applications in the regional delivery of highly potency therapeutics （这里不知道怎么翻好）to the lungs, as reliable delivery of small dosages may be more consistently achieved, since the drug is encapsulated within the water core, and adhesion between the walls of the container and the drug (when compared to drugs formulated as crystals) are less of a concern (Traini et al., 2006; Price et al., 2002). Reverse microemulsion-based formulations have other potential advantages over other suspension- and solution-based formulations in that they may provide an opportunity to deliver drug combinations (e.g. therapeutic biomolecules and or other small polar drug) without the need of extensive reformulation.

The relevance of this work stems from the fact that aqueous-based HFA-pMDIs are expected to be versatile formulations, with the ability to carry a range of medically relevant hydrophilic compounds within the nanocontainers, including high potency drugs, drug combinations and biomacromolecules.

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