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专业: 高分子材料结构与性能

[交流] 化学专业分析化学专业－－－任吉存教授

化学专业分析化学专业－－－任吉存教授

任吉存教授 (Prof. Jicun Ren)

任吉存教授 (博士），博士生导师。1994年于武汉大学获得分析化学专业博士学位。1994年7 月1996年3 月任湖南师范大学化学系副教授，并在湖南医科大学肿瘤研究所从事博士后研究工作。1996 年3 月至2000 年3月在挪威Bergen大学参加欧共体重大基金项目研究，1997年破格晋升教授。2001年起任上海交通大学化学化工学院教授，博士生导师。在国内外权威及核心期刊如  Angew. Chem. Int. Ed., Analytical Chemistry, Journal of Physical Chemisry B, Human Mutation，Clinical Chemistry, Current Medical Chemistry, Chemical Communication,  Trends in Analtical Chemistry, Electrophoresis，Journal of Chromatography A, 等发表论文90余篇，参与美国Humana 出版《Capillary Electrophoresis of Nucleic Acids》撰写工作。现任中国仪器学会微分析仪器专业委员会委员, 《生命科学研究》杂志编委。

研究方向
生物分析化学。主要包括: 高效毛细管电泳,微流控芯片，单分子探测(荧光相关光谱（FCS）和全内反射荧光成像技术（TIRFM）），单细胞分析，纳米生物技术(功能化纳米材料合成及其在生物分析中的应用）。

目前主持的研究项目主要包括：国家自然科学基金重点项目(1项)，国家自然科学基金重大研究计划(1项)，国家自然科学基金面上项目(1项)，863 专项(1项)，上海市农委重大攻关项目(1项)，上海市自然科学基金项目(1项)，教育部及人事部留学归国人员启动基金项目(各1项)及与挪威Bergen大学合作项目等(1项)。

近期发表的部分论著 (Selected Publications)

论文 (Papers)

Hua He, Huifeng Qian, Chaoqing Dong, Kanglin Wang，Jicun Ren*, Single Nonblinking CdTe Quantum Dots Synthesized in Aqueous Thiopropionic Acid, Angew. Chem. Int. Ed. 2006, 45, 7588-7591.

Qing Zhi, Chao Xie, Jicun Ren*，Coupling chemiluminescence detection with capillary electrophoresis to to analyze single human red blood cells, 2007, Anal. Chim. Acta, in press.

Xiangyi Huang, Liang Li, Huifeng Qian, Chaoqing Dong, Jicun Ren* A Resonance Energy Transfer between Chemiluminescence Donors and CdTe Quantum Dots Acceptors (CRET), Angew. Chem. Int. Ed., 2006, 45, 5140 –5143.

Fuming Sang, Haixia Ren, Jicun Ren* Genetic Mutation Analysis by Capillary Electrophoresis with Laser-Induced Fluorescence Detection Using Inverse Flow Derivatization of DNA Fragments, Electrophoresis, 2006, 27,3846–3855.

Chaoqing Dong, Pudun Zhang, Rui Bi, Jicun Ren* Characterization of solution-phase DNA hybridization by fluorescence autocorrelation spectroscopy: genotyping of C677T from methylene tetrahydrofolate reductase gene, Talanta, 2006, 70, in press.

Xiaofeng Qu, Fuming Sang, Jicun Ren* Fabrication of PDMS/Glass Microchip by Twice Replica Molding of PDMS and Its Applications, J. Sep. Sci., 2006, 29, 2390 – 2394.

Chaoqing Dong, Huifeng Qian, Nenghu Fang and Jicun Ren*, Study of Fluorescence Quenching and Dialysis Process of CdTe Quantum Dot Using Ensemble Techniques and Fluorescence Correlation Spectroscopy, J. Phys. Chem. B, 2006, 110,11069-11075.

Fuming Sang, Jicun Ren* Comparisons between Capillary Zone Electrophoresis and Real Time PCR for Quantification of cell-free DNA in Human Sera, J. Chromatogr. B, 2006, 838, 122-128.

Liang Li, Jicun Ren*, Rapid preparation of spinel Co3O4 nanocrystals in aqueous phase by microwave irradiation, Materials Research Bulletin, 2006, 41, 2286–2290.

Huifeng Qian, Xing Qiu, Liang Li, Jicun Ren* Microwave assisted aqueous synthesis: a rapid approach to prepare highly luminescent ZnSe(S) alloyed quantum dots， J. Phys. Chem. B, 2006, 110, 9034-9040.

Liang Li, Jicun Ren*, Aqueous synthesis of CdTe@FeOOH  and CdTe@Ni(OH)2  composited nanoparticles，J. Solid State Chem. 2006, 179, 1814-1820.

Jifang Weng, Jicun Ren*, Luminescent Quantum Dots:  An Attractive Promising Tool in Biomedicine, Current Medicinal Chemistry, 2006, 13, 897-909.

Huifeng Qian, Jicun Ren*, Facile one-pot synthesis of highly luminescent, water-soluble and bio-compatible glutathione coated CdTe quantum Dots in aqueous phase, Small, 2006, 2,747-751.

Jifang Weng, Xingtao Song, Liang Li, Keying Chen, Xueming Xu and Jicun Ren*  Highly Luminescent CdTe Quantum Dots Prepared in Aqueous Phase as An Alternative Fluorescent Probe for Cell Imaging, Talanta, 2006, 70, 397-404.

Fuming Sang, Jicun Ren* Capillary electrophoresis of dsDNA fragments using new fluorescence dye-EvaGreen as a DNA intercalating dye, J. Sep. Sci., 2006, 29, 1275-1280.

Rui Bi, Jicun Ren* Combination of Micro-fluidic Chip with Fluorescence Correlation Spectroscopy for Single Molecule Detection, Chin Chem. Lett. 2006, 17,521-524.

Xingtao Song, Liang Li, Huifeng Qian and Jicun Ren*, Highly Efficient Size-Dependent Separation of CdTe Quantum Dots by Capillary Gel Electrophoresis Using Polymer Solution as Sieving Medium, Electrophoresis, 2006，27, 1341-1346.

Xiangyi Huang, Jifang Weng, Chengxi Cao, Jicun Ren*, Characterization of quantum dots bioconjugates by capillary electrophoresis with laser-induced fluorescence detector, J. Chromatogr. A, 2006, 1113, 251-254.

Xiangyi Huang, Jicun Ren*,  Chemiluminescence detection in capillary electrophoresis and microchip capillary electrophoresis,  TRAC：Trends in Analytical Chemistry, 2006,25,155-156.

Chaoqing Dong, Rui Bi, Huifeng Qian, Jicun Ren* Coupling fluorescence correlation Spectroscopy with Microchip Electrophoresis to Determine Effective Surface Charge of Water-Soluble QDs, Small, 2006, 2,534-538.

Yining Zheng, Yang Sun, Jicun Ren*，Identification and Quantitation of iodotyrosines and iodothyronines in hydrolysate of iodinated casein by capillary electrophoresis, Talanta,2006, 69,107-112.

Liang Li, Huifeng Qian, Nenghu Fang, Jicun Ren*, Significant Enhancement of the Quantum yield of CdTe Nanocrystals synthesized in aqueous phase by controlling the pH and concentrations of precursor solutions, J. Luminesc., 2006, 116, 59-66.

Liang Li, Huifeng Qian, Jicun Ren*，    CdTe@Co(OH)(core/shell) nanoparticles: aqueous synthesis and characterizations,       Chemical Communication,2005, 4083 - 4085.

Pudun Zhang, Liang Li, Chaoqing Dong, Huifeng Qian, Jicun Ren* Sizes of Water-Soluble Luminescent Quantum Dots Measured by Fluorescence Correlation Spectroscopy, Analytica Chimca Acta, 2005, 546: 46–51.

Xiangyi Huang, Jicun Ren* On-line chemiluminescence detection for isoelectric focusing of heme proteins on microchips, Electrophoresis, 2005, 26, 3595–3601.

Huifeng Qian, Liang Li, Jicun Ren* One-pot aqueous synthesis of high quality alloyed quantum dots (CdSe-CdS) by microwave irradiation with controllable temperature, Materials Research Bulletin，2005， 40, 1726-1736.

Jiaoning Wang, Jicun Ren*, A Sensitive and Rapid Immunoassay for Quantification of CA125 in Human Sera by Capillary Electrophoresis with Enhanced Chemiluminescence Detection, Electrophoresis, 2005, 26, 2402–2408.



Liang Li, Huifeng Qian, Jicun Ren*, Rapid Synthesis of Highly Luminescent CdTe Nanocrystals in Aqueous Phase by Microwave Irradiation with Controllable Temperature, Chemical Communication, 2005, 528-530.

Nenghu Fang,* Li Lin, Jicun Ren and Dan Wu, Detection of C677T mutation in methylenetetrahydrofolate reductase gene by denaturing high performance liquid chromatography, Biomedical  Chromatography, 2004, 18: 625-629.

Peng Zhang, Jicun Ren*, A new quantitative method for  circulation DNA Levels in human serum by capillary zone electrophoresis with laser-induced fluorescence detection, Electrophoresis, 2004, 25(12): 1823 – 1828.

Lin Chen, Jicun Ren* et al., Ultraviolet sealing and poly(dimethylacrylamide) modification for poly(dimethylsiloxane)/glass microchips, Electrophoresis, 2004, 25(6):914-21.

Lin Chen, Jicun Ren* ,  High-throughput DNA analysis by microchip electrophoresis, Comb Chem High Throughput Screen. 2004 , 7(1): 29-43

Ping Wang, Jicun Ren*, Separation of purine and pyrimidine bases by capillary electrophoresis using beta-cyclodextrin as an additive, J. Pharm. Biomed. Anal. 2004, 34(2): 277-83.

Peng Zhang, Jicun Ren*,  Study of polydimethylacrylamide - and polydiethylamide adsorbed coating on fused silica capillaries and their applications in genetic analysis, Analytica Chimca Acta, 2004, 507: 179-184.

Xiangyi Huang, Jicun Ren*, Capillary Electrophoresis of polyamine with universal indirect chemiluminescence detection using cobalt(II) as a prob ion, Journal of Liquid Chromatography & relatied technologies, 2003, 26: 355-36.

Jicun Ren*, Arve Ulvik, Helga Refsum, Per Magne Ueland , Uracil in Human DNA from Subjects with Normal and Impaired Folate Status, as Determined by High Performance Liquid Chromatography-Tandem Mass, Analytical Chemistry, 2002, 74: 295-299.

Jicun Ren*, Nenghu Fang, Dan Wu,Inverse-flow derivatization for capillary electrophoresis of DNAfragments with laser-induced fluorescence detection,  Analytica Chimca Acta, 2002, 470: 129-135.

Jicun Ren*, Nenghu Fang, Dan Wu, Effects of polyols, pH and electrolyte concentrations in TBE buffer on separation of double strand DNA fragments by capillary electrophoresis,  Analytical Science, 2002, 18：469-471.

Jicun Ren*, Xiangyi Huang, Highly Sensitive and Universal Indirect Chemiluminescence Detection for Capillary Electrophoresis of Cations Using Cobalt(II) As A Novel Probe Ion,  Analytical Chemistry, 2001, 73, 2663-2668.



著作 (Book Chapters)

Jicun Ren, 《Capillary Electrophoresis of Nucleic Acid》, Chapter 10 and Chapter 19, Jan., 2001, Humana Press Inc., Totowa, NJ, USA.

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