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猜猜这是文献还是书！
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就这么多信息 ，不知道是文献还是一本书 ，希望牛人帮我看看！说出点门道给5个金币，查出来给20个！金币不重要，助人为乐！ 希望斑竹放行一段时间！谢谢了！ Antidiabetic Drugs, HPLC/TLC Determination of Authors: A. Gumieniczek a; H. Hopka a a; A. Berecka a Affiliation: a Department of Medicinal Chemistry, Medical University. Lublin. Poland DOI: 10.1081/E-ECHR-120042796 Editor: Published in: Encyclopedia of Chromatography Published on: 27 March 2006 Subject: Analytical Chemistry; Formats available: HTML (English) : PDF (English) Purchase Section: US$12.50 - buy now add to cart · Sign In Abstract A review of some chromatographic methods for determination of new oral antidiabetic drugs is presented: gliclazide, glimepiride, and glipizide from sulfonylureas; nateglinide and repaglinide from glinides; and pioglitazone and rosiglitazone from glitazones. This entry describes the selected methods for the analysis of these important drugs in pharmaceuticals and in biological materials. Two chromatographic techniques [High-performance liquid chromatography (HPLC), Thin-layer chromatography (TLC)] and various pretreatment modes are described. Sensitivities, linearities, and specificities of the presented methods are compared. The selected methods for determination of potential impurities in bulk drug substances and metabolites of the drugs in biological samples are described. Stability data concerning the mentioned drugs are also presented. Finally, suitable methods for separation of the drugs as well as their isomers (enantiomers and diastereoisomers) are presented. Keywords: Antidiabetic drugs; HPLC; TLC; Separation view references (25) |
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