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yyt_99

木虫 (正式写手)

[求助] 求助雷贝拉唑在Thomson pharma数据库还有默克索引中的检索结果

求助雷贝拉唑在Thomson pharma数据库还有默克索引中的检索结果,最好是输出WORD的形式,给个清晰的截图也行,上传下文件,麻烦了,着急。
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做个小学生,好好看文献
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zhanyf

木虫 (小有名气)

【答案】应助回帖


感谢参与,应助指数 +1
marktiger: 金币+1, 谢谢参与,欢迎常来。 2012-11-12 08:32:23
默克索引如下:
Title: Rabeprazole
CAS Registry Number: 117976-89-3
CAS Name: 2-[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
Additional Names: pariprazole
Molecular Formula: C18H21N3O3S
Molecular Weight: 359.44
Percent Composition: C 60.15%, H 5.89%, N 11.69%, O 13.35%, S 8.92%
Literature References: Partially reversible gastric proton pump inhibitor. Prepn: S. Souda et al., EP 268956; eidem, US 5045552 (1988, 1991 both to Eisai). Pharmacology: H. Goto et al., Arzneim.-Forsch. 41, 635 (1991). Mode of action: M. Morii, N. Takeguchi, J. Biol. Chem. 268, 21553 (1993). HPLC determn in plasma: H. Nakai et al., J. Chromatogr. B 660, 211 (1994). Clinical pharmacokinetics: S. Yasuda et al., Int. J. Clin. Pharmacol. Ther. 32, 466 (1994). Review of clinical trials in acid peptic diseases: M. L. Cloud et al., Dig. Dis. Sci. 43, 993-1000 (1998); of pharmacology and clinical experience in gastro-esophageal reflux disease: B. Thjodleifsson, Expert Opin. Pharmacother. 5, 137-149 (2004).
Properties: White crystals from CH2Cl2/ether, mp 99-100° (dec).
Melting point: mp 99-100° (dec)

Derivative Type: Sodium salt
CAS Registry Number: 117976-90-6
Manufacturers' Codes: E-3810
Trademarks: Aciphex (Eisai); Pariet (Eisai)
Molecular Formula: C18H20N3NaO3S
Molecular Weight: 381.42
Percent Composition: C 56.68%, H 5.29%, N 11.02%, Na 6.03%, O 12.58%, S 8.41%
Properties: White crystals from ether, mp 140-141° (dec). Very sol in water, methanol; freely sol in ethanol, chloroform, ethyl acetate. Insol in ether, n-hexane.
Melting point: mp 140-141° (dec)

Therap-Cat: Antiulcerative.
Keywords: Antiulcerative; Gastric Proton Pump Inhibitor.
3楼2012-11-11 23:26:51
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hkp

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这个数据在哪里能找到啊?
2楼2012-11-11 21:36:45
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cpujacs

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【答案】应助回帖

感谢参与,应助指数 +1
单单一个TP20金币就没有人应助,估计要100才能吸引眼球
4楼2012-11-12 08:30:37
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ChemInfo-VIP

铁虫 (初入文坛)

【答案】应助回帖

感谢参与,应助指数 +1
5楼2012-11-12 10:10:54
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