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[资源] Handbook of Combinatorial Chemistry: Drugs, Catalysts, Materials (2-Vol. Set)

Review:
â?œâ?¦an up-to-date, authoritative, comprehensive reference source that should be indispensable for synthetic, organic and medicinal chemists; chemical biologists; and material scientists.â? (The Chemical Educator, Vol. 10, No. 4. 2005)

"'Handbook of Combinatorial Chemistry,' a comprehensive and timely information resource, would be a valuable reference for scientists in the fields of synthetic, organic and medicinal chemistry, as well as chemical biology and material science.â? (E-Streams, Vol. 7, No. 5)

"...the editors have succeeded in guiding the many authors from different backgrounds to write a largely coherent and readable standard work of combinatorial chemistry, which keeps the promises given in its title." (Angewandte Chemie)

"...an excellent contribution to the field of research..." (Chemistry & Industry, 6 January 2003)

"...this book is a valuable and rich source of information..." (Perkin Transactions, Vol.1, No.23, 2002)

"...it is an excellent reference book that most researchers in the field will want on their bookshelves and/or in their library...." (Synthesis, No. 7, 2003)

r
"...this book is a valuable and rich source of information..."

Product Details:

Hardcover: 1145 pages
Publisher: Wiley-VCH; 1st edition (May 24, 2002)
Language: English
ISBN: 3527305092

posted by design 163 days ago
Table of Contents

GENERAL ASPECTS
Combinatorial Chemistry in Drug Discovery
Principles of Combinatorial Chemistry
Solid and Soluble Supports for Heterogenous Systems
Linkers for Solid Phase Synthesis
Encoding Technologies
Instrumentation for Combinatorial Chemistry

SYNTHETIC CHEMISTRY
Radical Chemistry
Nucleophilic Substitution
Electrophilic Substitution
Elimination
Addition to CC Multiple Bonds Except CC Bond Formation
Addition to CX Multiple Bonds Except CO Double Bonds
Chemistry of the Carbonyl Group
Oxidation Except CC Double Bonds
Reduction Except CC Double Bonds
Cycloaddition
Main Group Organometallics
Enolates and Related Species
Transitions Metal Catalyzed Formation of Single Bonds
Metathesis and Related Processes for CC Multiple Bond Formation

SPECIAL SYNTHETIC TOPICS
Libraries of Natural Products
Synthesis of Heterocyclic Systems
Multicomponent Reactions
Combinatorial Chemistry of Oligosaccharides

DESIGN OF COMBINATORIAL LIBRARIES
Design Criteria
Estimation of Physicochemical Parameters
Virtual Libraries and Modeling
Case Study: Medicinal Chemistry

NOVEL APPLICATIONS OF COMBINATORIAL CHEMISTRY
Combinatorial Chemistry in the Fine Chemical Industry
High Throughput Process Research
Combinatorial Approaches to Catalyst Discovery
Case Study: Combinatorial Catalyst Discovery
Combinatorial Aspects of Material Research
Combinatorial Principles of Biology and Their Potential Applications to Drug Discovery
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