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Wnt Signaling Volume 2 Pathway Models
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Detailed item info Product Identifiers ISBN-10 1603274685 ISBN-13 9781603274685 Key Details Series Methods in Molecular Biology Publication Date 2008-10-15 Language English Publisher's Note Since their discovery, Wnt signaling molecules have been shown to control key events in embryogenesis, to maintain tissue homeostasis in the adult and, when aberrantly activated, to promote human degenerative diseases and cancer, thus making them a vital area of study. Wnt Signaling: Methods and Protocols examines both biochemical assays and vertebrate and invertebrate model systems to provide a point of reference to current molecular protocols and the diverse model systems employed to study this important signaling pathway. In Volume 2, Pathway Models, the diverse vertebrate and invertebrate models that have shaped the Wnt signaling field are described, presenting an overview of the unique properties of each organism, like asymmetric cell division in C. elegans and epithelial morphogenesis in Dictyostelium, with respect to studying Wnt/FZD function. As a volume in the highly successful Methods in Molecular Biologyâ?¢ series, chapters contain readily reproducible laboratory protocols, complete with lists of necessary equipment and reagents and the Notes section, which reveals helpful troubleshooting tips.Comprehensive and cutting-edge, Wnt Signaling: Methods and Protocols collects the expertise and knowledge of many leaders in the field to produce this invaluable two-volume resource., The second book in this two-volume series on Wnt signaling molecules describes vertebrate and invertebrate models of study such as asymmetrical cell division in C. elegans and epithelial morphogenesis in Dictyostelium. Editor Vincan (anatomy and cell biology, U. of Melbourne) has collected research from scientists in the field to explain the Wnt/FZD functions of these organisms and to build upon the signal pathway fundamentals explored in the first volume. Laboratory protocols, materials lists and troubleshooting tips are supplied for students and researchers in the fields of cell biology, medicine and associated disciplines. Annotation ©2009 Book News, Inc., Portland, OR (booknews.com)  cover.jpg |
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2012-10-29 08:42:35, 5.42 M
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