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[资源] Progress in Polymer Science综述，有关磁性高分子纳米材料

知名杂志Progress in Polymer Science，磁性纳米材料综述：Iron oxide-based superparamagnetic polymeric nanomaterials: Design, preparation, and biomedical application

[Abstract] Recent advances in the development and biological applications of polymeric nanomaterials embedded with superparamagnetic iron oxide nanoparticles (SIONPs) are summarized. Novel SIONP-polymer hybrid nanoparticles are prepared by various methods, including direct modiﬁcation with polymers, surface-initiated controlled polymerization, inorganic silica/polymer hybridization, self-assembly, self-association, and various heterogeneous polymerization methods. They have potential for various biomedical applications, including
magnetic resonance imaging (MRI) contrast enhancement, targeted drug delivery, hyperthermia, biological separation, protein immobilization, and biosensors.

Contents
1. Introduction ......................................................................................169
2. Synthesis of superparamagnetic iron oxide nanoparticles (SIONPs) .... 170
3. Direct modiﬁcation with polymers........................................................171
4. Surface-initiated controlled polymerization: “grafting from” method ....173
5. Inorganic silica/polymer hybridization. . . . . . . . . . . . . . . . . . . . . . . . .. 174
6. Self-assembly and self-association. . . . . . . . . . . . . . . . .. . .. . .. . .. . .. .175
7. Heterogeneous polymerization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 176
7.1. Inverse (mini)emulsion polymerization . . . . . . . . . . . . . . .. . .. . . . . . 176
7.2. Dispersion polymerization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . .178
7.3. Other heterogeneous polymerization methods . . . . . . . . .  . . .. . .. . 179
8. Bulk physical and chemical crosslinking – magnetic hydrogel preparation. . . . . . . . . . . . . . . .. . .. . .. . .. . .. . .. . .. . .. . .. . .. . .. . .. . .. 179
9. Bio-applications of SIONP-polymer hybrids . . . . . . . .. . .. . .. . .. . .. . .  179
9.1. MR imaging . . . . . . . . . . . . .. . .. . .. . .. . .. . .. . .. . .. . .. . .. . .. . . . .  179
9.2. Drug delivery . . . . . .  . . . . . . . . . . . . . . .. . .. . .. . .. . .. . .. . .. . .. .. .181
9.3. Other applications including hyperthermia, protein immobilization, and catalysis. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . .. . .. . .. . .. . . 183
10. Conclusion . . . . .. . . . . . . . . . . . .. . .. . .. . .. . .. . .. . .. . .. . .. . .. .. . . .184
Acknowledgement . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . .. . .. . .. . .. . .184
References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . .. . .. . .. . .. .  . 184

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