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xcs320721木虫之王 (知名作家)
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[求助]
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聚乳酸及其共聚物偶联抗体不仅可以抑制癌细胞的增殖,诱导其凋亡,还可以靶向到病变部位,是一类可实现药物缓释,生物性能优良的材料。此文简要介绍了几种易与胃癌细胞表面高表达抗原相结合的单抗及其各自的靶向机理。另外, 比较并分析了靶向纳米粒和非靶向纳米粒的抗肿瘤效果。最后笔者结合实际工作经验, 提出了尚需解决的几点问题。 [ Last edited by xcs320721 on 2012-7-16 at 20:36 ] |
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huairpan
木虫 (正式写手)
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【答案】应助回帖
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Mally89: 金币+1, 感谢应助! 2012-07-17 20:11:17
xcs320721: 金币+80, 翻译EPI+1, ★有帮助, 就用你了,谢谢 2012-07-21 17:15:38
Mally89: 金币+1, 感谢应助! 2012-07-17 20:11:17
xcs320721: 金币+80, 翻译EPI+1, ★有帮助, 就用你了,谢谢 2012-07-21 17:15:38
| Conjugated antibodies for poly lactic acids and the copolymers thereof are such materials that can achieve the drug slowly release with well biological properties. The conjugated antibodies can not only inhibit the proliferation of the tumor cells, but also can induce the apoptosis thereof. The text also introduces several kinds of monoclonal antibodies specifically binding with the antigens highly expressed on the surfaces of the gastric cancer cells, as well as their respective targeting mechanisms. In addition, the anti-tumor effects of the targeted nanoparticles and non-targeted nanoparticles are compared and analyzed. At last, in combination with the work experiences the author points out several issues to be solved. |

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