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[求助]
请帮忙翻译几句关于生物医药方面的英文，谢谢~
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Also, Fas (fatty acid synthase) or aP2 (adipocyte fatty-acid-binding protein 2), which are both expressed in adipocytes, are known to be involved in insulin resistance. Fas is expressed in an early stage of adipocyte differentiation and functions to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA. Fas plays a role in the storage of surplus energy in the form of triglycerides, which may cause obesity. The resulting triglyceride palmitate destroys pancreatic β cells to induce insulin resistance。 To examine whether the compounds of Chemical Formulas 1 and 2, which are the active ingredients for improving obesity, can be used as anti-insulin resistance agents, they were applied to adipocytes which were then quantitatively analyzed for resistin, a lipocytokine involved in insulin resistance, and Fas and aP2. To examine whether the samples are effective as anti-insulin resistance agents, expression levels of resistin, aP2 and Fas in the cells that had been differentiated for 8 days as in Experimental Example 1 were analyzed using the primers of Table 2, below. |
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爱与雨下: 金币+1 2012-06-18 21:11:14
scswpiyly: 金币+15, 翻译EPI+1, ★★★★★最佳答案, thanks！ 2012-06-21 08:50:19
爱与雨下: 金币+1 2012-06-18 21:11:14
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另外，脂肪细胞表达的脂肪酸合成酶(FAS)或脂肪细胞脂肪酸结合蛋白2(AP2)参与胰岛素抵抗。 FAS在分化早期阶段脂肪细胞中表达，其功能是催化乙酰辅酶A和丙二酰辅酶A合成棕榈酸酯。FAS还促进多余的能量以甘油三酯的形式储存，这可能会导致肥胖。随之产生的棕榈酸甘油酯破坏胰岛β细胞诱导胰岛素抵抗。 为了检测符合化学公式1和2的化合物（改善肥胖有效成分）是否可作为抗胰岛素抵抗药物，应用它们作用脂肪细胞，然后定量分析他们对抵抗素（涉及胰岛素抵抗的脂肪细胞因子）、FAS和AP2表达的影响。 为了检测样品和抗胰岛素抵抗剂是否具有同样效果，按实验例1中方法分化细胞8天，然后应用下面表2中引物对细胞中抵抗素、AP2和FAS表达水平进行分析。 |
2楼2012-06-18 17:03:08