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[求助]
请帮忙翻译一段关于生物医药方面的英文,谢谢~
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If there is any later exposure to the same allergen, the allergen can bind to the IgE molecules heldon the surface of the mast cells. Cross-linking of the IgE and FcεRI occurs when more than one IgE-receptor complex interacts with the same allergenic molecule, and activates the sensitized cell, triggering a signal transduction pathway. Activated mast cells undergo a process called degranulation, during which they release histamine and other inflammatory chemical mediators including proteoglycans, proteases, leukotrienes, prostaglandins and cytokines, which are already present or synthesized anew, from their granules into the surrounding tissue, causing several allergic reactions, such as vasodilation, nerve stimulation, mucous secretion, and smooth muscle contraction. |
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scswpiyly: 金币+15, 翻译EPI+1, ★★★★★最佳答案, thanks! 2012-06-15 16:55:53
scswpiyly: 金币+15, 翻译EPI+1, ★★★★★最佳答案, thanks! 2012-06-15 16:55:53
| 如果有任何之后暴露的相同过敏原,则过敏原可结合IgE分子附着在肥大细胞的表面上。当一个以上的IgE受体复合物与相同的过敏分子相互作用时,IgE 和FcεRI产生交联,并激活致敏细胞,激起信号转导通路。激活肥大细胞的过程称为脱颗粒,是肥大细胞从他们的颗粒中向周围组织释放已有或者重新合成的组胺以及其他炎症化学媒介包括蛋白聚糖、蛋白酶、白细胞三烯、前列腺素和细胞激素的过程,引起若干炎症反应,比如血管舒张、神经刺激、粘液分泌以及平滑肌收缩。 |

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