| 查看: 942 | 回复: 4 | ||
| 本帖产生 1 个 翻译EPI ，点击这里进行查看 | ||
1121prettycat木虫 (正式写手)
|
[求助]
求助一段话翻译
|
|
| 影响化合物在机体中分布的因素很多，主要有药物的脂溶性、毛细血管通透性、器官和组织的血流量、与血浆蛋白和组织蛋白的结合率等。暴露期结束时，肺脏中AHTN含量最高，尤其是中、高剂量的AHTN暴露后，肺脏中AHTN的含量远远高于其它组织，表明肺脏是AHTN在体内的主要蓄积器官。至于AHTN为什么会在肺中有较高分布，是否是由于肺脏中的血流量大、AHTN能否与肺细胞表面的某些特异性受体结合以及会带来哪些影响，还需要作进一步的研究。肝脏和肾脏中有较高的AHTN分布，提示AHTN有可能通过肾脏和肝脏的排泄作用而被清除出体外。心脏中检测到较高浓度的AHTN，主要是由于心脏的血流量大的缘故。脑组织中AHTN的含量高于血液中AHTN的含量，表明AHTN能穿过血脑屏障，进而在脑组织中蓄积，这可能是因为AHTN的分子量相对较小，脂溶性高引起的。此外，尽管睾丸的血流量要低于其它组织，但是由于睾丸中脂肪含量相对较高，其对脂溶性较强的AHTN也有一定的蓄积能力。 |
回复此楼» 本帖@通知
@爱与雨下
» 猜你喜欢
filecode
已经有16人回复
-
基金中了
已经有9人回复
-
听说今天filecode变了
已经有39人回复
-
固定端突然变了，今天
已经有8人回复
-
filecode
已经有11人回复
-
大家散了吧，后缀研究没有意义，别浪费时间了，过好目前的每一天，不要焦虑
已经有6人回复
-
一个有机合成实验室都需要哪些设备？
已经有12人回复
-
求各位大神看下
已经有33人回复
-
咨询面上基金
已经有7人回复
-
影响面上的因素
已经有11人回复
jeangong
木虫之王 (文学泰斗)
- 翻译EPI: 8
- 应助: 129 (高中生)
- 金币: 68743.7
- 散金: 4
- 红花: 54
- 帖子: 56257
- 在线: 813.8小时
- 虫号: 222140
- 注册: 2006-03-21
- 专业: 无机材料化学
【答案】应助回帖
★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ★ ...
爱与雨下: 金币+2 2012-06-10 19:19:41
1121prettycat: 金币+40, 翻译EPI+1, ★有帮助 2012-06-12 11:43:31
sltmac: 金币+50 2012-07-24 11:07:58
sltmac: 金币+20 2012-07-24 11:08:04
爱与雨下: 金币+2 2012-06-10 19:19:41
1121prettycat: 金币+40, 翻译EPI+1, ★有帮助 2012-06-12 11:43:31
sltmac: 金币+50 2012-07-24 11:07:58
sltmac: 金币+20 2012-07-24 11:08:04
|
There are many factors that affect the compounds in the distribution in the body, such as lipid-soluble of drugs, capillary permeability, blood flow to organs and tissues, and plasma protein and tissue protein binding rate and so on. There are the highest AHTN content in the Lung afer exposure period, especially after exposure to medium and high doses of AHTN, the content of the lungs AHTN is much higher than other organizations, whichi showed that the lung is the main accumulation AHTN organs of the body. Why AHTN in the lungs have a higher distribution, whether it is due to the blood volume in the lungs, or the AHTN whether the surface of the lung cells of certain specific receptor binding and what impact, these need the further research. Liver and kidney have a higher the AHTN distribution, which suggested that the the AHTN there may excretion through the kidneys and liver were removed from the in vitro. Detected the higher concentrations of AHTN in the heart, which mainly caused due to the big blood flow volume of the heart's. The content of AHTN in brain tissue is higher than those of in the blood, showed that AHTN can through the blood-brain barrier, and thus accumulate in the brain, which may be caused because of the AHTN's relatively small molecular weight, fat-soluble high. In addition, although the testicular blood flow is lower than other organizations, but the fat content is relatively high due to the testis, and its accumulation on the fat-soluble strong AHTN. |
2楼2012-06-10 15:14:25
sesame_oil
荣誉版主 (文坛精英)
- 翻译EPI: 8
- 应助: 4518 (副教授)
- 贵宾: 2.947
- 金币: 35328.4
- 散金: 385
- 红花: 188
- 沙发: 2
- 帖子: 18585
- 在线: 536.5小时
- 虫号: 1188734
- 注册: 2011-01-12
- 专业: 计算机应用技术
- 管辖: 论文投稿
【答案】应助回帖
★ ★ ★ ★ ★
爱与雨下: 金币+2 2012-06-10 19:19:51
book2005593: 金币-7, google在线翻译，收回奖励并按规定扣5金币！ 2012-06-11 15:41:47
book2005593: 违规存档, 违规用goole在线翻译~ 2012-06-11 15:45:13
爱与雨下: 金币+2 2012-06-10 19:19:51
book2005593: 金币-7, google在线翻译，收回奖励并按规定扣5金币！ 2012-06-11 15:41:47
book2005593: 违规存档, 违规用goole在线翻译~ 2012-06-11 15:45:13
| There are many factors affect the compounds in the distribution in the body, mainly the fat-soluble drugs, capillary permeability, blood flow to organs and tissues, and plasma protein and tissue protein binding rate and so on. The end of the exposure period, AHTN content in the lungs of the highest, especially after exposure to high doses of AHTN, the content of the lungs AHTN is much higher than other organizations, suggesting that lung AHTN main accumulation organ in the body.Why As for AHTN in the lungs have a higher distribution, whether it is due to the blood volume in the lungs, the AHTN whether the surface of the lung cells of certain specific receptor binding and what impact, the need for further research.Liver and kidney have a higher the AHTN distribution, suggesting that the the AHTN there may excretion through the kidneys and liver were removed from the in vitro.Detected in higher concentrations of AHTN in the heart, mainly due to the blood flow volume of the heart's sake.AHTN the content is higher than the content of AHTN blood in brain tissue, showed that AHTN through the blood-brain barrier, and thus accumulate in the brain, which may be because it the AHTN's relatively small molecular weight, fat-soluble high caused.In addition, although the testicular blood flow is lower than other organizations, but the fat content is relatively high due to the testis, and its accumulation on the fat-soluble strong AHTN. |
3楼2012-06-10 15:38:19
1121prettycat
木虫 (正式写手)
- 应助: 0 (幼儿园)
- 金币: 3426.2
- 散金: 53
- 帖子: 420
- 在线: 130.6小时
- 虫号: 366596
- 注册: 2007-05-10
- 性别: MM
- 专业: 环境分析化学
4楼2012-06-10 23:23:10
book2005593
主管区长 (文坛精英)
- 翻译EPI: 3
- 应助: 123 (高中生)
- 贵宾: 64.97
- 金币: 161270
- 散金: 12654
- 红花: 246
- 沙发: 183
- 帖子: 17949
- 在线: 1647.8小时
- 虫号: 539655
- 注册: 2008-04-04
- 专业: 应用数学方法
- 管辖: 学术交流区
5楼2012-06-11 15:38:36
50