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ludou2009

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[交流] 推荐一篇2011年发在Nano Letter上的基于表面等离激元共振效应的生物化学传感器 已有1人参与

ABSTRACT: In this work, we report the design, fabrication,
and characterization of novel biochemical sensors consisting of
nanoscale grooves and slits milled in a metal film to form twoarm,
three-beam, planar plasmonic interferometers. By
integrating thousands of plasmonic interferometers per square
millimeter with a microfluidic system, we demonstrate a sensor
able to detect physiological concentrations of glucose in water
over a broad wavelength range (400−800 nm). A wavelength
sensitivity between 370 and 630 nm/RIU (RIU, refractive
index units), a relative intensity change between ~103 and 106
%/RIU, and a resolution of ~3 × 10−7 in refractive index change were experimentally measured using typical sensing volumes as
low as 20 fL. These results show that multispectral plasmonic interferometry is a promising approach for the development of
high-throughput, real-time, and extremely compact biochemical sensors.
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