Thank you for submitting your manuscript entitled XXX to the
Journal of Biological Chemistry. Your manuscript has been carefully reviewed by a member of the Editorial Board and an outside expert in the field. I am sorry to report that the decision was made to decline the manuscript in its current form. You will note from the reviewers' comments below that reviewer 2 has some serious concerns XXX. Given these concerns I regret that I must decline your manuscript. I would be willing to consider a revised manuscript that XXX. Note that no guarantee of acceptance of the revised manuscript is implied.
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