| 查看: 275 | 回复: 6 | |||
| 【奖励】 本帖被评价6次，作者darliu增加金币 5.5 个 | |||
| 当前主题已经存档。 | |||
[资源]
A Statistical Mechanical Approach to Combinatorial Chemistry
|
|||
|
Author: Michael W. Deem language : English format: Pdf April 9, 2006 An analogy between combinatorial chemistry and Monte Carlo computer simulation is pursued. Examples of how to design libraries for both materials discovery and protein molecular evolution are given. For materials discovery, the concept of library redesign, or the use previous experiments to guide the design of new experiments, is introduced. For molecular evolution, examples of how to use ``biased' Monte Carlo to search the protein sequence space are given. Chemical information, whether intuition, theoretical calculations, or database statistics, can be naturally incorporated as an a priori bias in the Monte Carlo approach to library design in combinatorial chemistry. In this sense, combinatorial chemistry can be viewed as an extension of traditional chemical synthesis. http://babbage.sissa.it/PS_cache/cond-mat/pdf/0009/0009243.pdf |
回复此楼» 猜你喜欢
什么脱膜剂可以完全清洗干净啊？
已经有2人回复
-
暨南大学化学与材料学院赵宇亮院士正在招博士和博后，方向为生物材料和纳米医学
已经有1人回复
-
有机高分子材料论文润色/翻译怎么收费?
已经有90人回复
-
可生物降解聚酯正在重塑现代医疗器械
已经有0人回复
-
26届博士申请
已经有2人回复
-
PLLA 微球在生物医学领域的研究与应用
已经有1人回复
-
PLLA 微球的材料特性与制备工艺解析
已经有0人回复
-
医用聚己内酯（PCL）全解析：从两段式降解到组织工程应用
已经有0人回复
-
反相硅胶如何再生？
已经有1人回复
2楼2007-02-17 09:26:17
祝所有的小虫子们新春愉快！ 
3楼2007-02-17 14:20:36
30