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[求助]
翻译2小段英文（生理调控方向，新号金币不多）
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Hormones and neuronal signals might function as controlled variables in a cybernetic model. Hypothalamic neurons with binding sites of metabolic feedback signals and with contact to vagal afferents could function as sensors. Obviously, estrogens and monoaminergic afferents modulate the sensor sensitivity and integrate different aspects of homeostasis (e.g. thermogenesis and reproductive behavior) in the context of sensory stimuli and responses. This issue can be summarized under the concept of the nterplay of general arousal with different modules of behavior (e.g. feeding or mating behavior, nursing behavior) (45). Rodents have an increased response to sexual stimuli after priming with estrogens, whereas nutritional stimuli are neglected (46). The feedback signal is compared with the set point and the resulting control error is sent to the actuator after enhancement. Under consideration of the present experimental data, estrogens and monoaminergic afferents cannot provide the function of enhancement on feedback signals of food intake, because in this case the control error is enhanced independently of the direction of the error (too much or too little energy storage). Thus, the directional effects, enhancement or inhibition, on feeding behavior cannot be explained by estrogens and monoamines. More likely, estrogens and monoamines change the set point of the controller. In this way, a directional effect on feeding behavior becomes explicable, because the feedback loop drifts to less or more food intake when estrogens or monoamines are administered. [ Last edited by totti_fy on 2011-12-28 at 21:52 ] |
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2楼2011-12-29 00:02:44
