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PhD position on computational biology ÒÑÓÐ3È˲ÎÓë
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PhD Projects in Theoretical / Computational Biophysics Project 1: In Silico Analysis and Design of Protein-DNA Interaction Surfaces Problems: • DNA-binding proteins trigger conformational changes in DNA • Specificity of proteins for DNA sequences and structures are largely unknown Aims: • Analysis of protein-DNA interaction surfaces • Prediction of mutational effects on protein-DNA binding • Design of DNA-binding proteins with pre-defined specificities Project 2: Effect of General Anesthetics on Biological Membranes Studied in Simulations Problems: • Molecular mechanisms underlying the effect of anesthetics largely unknown Aims: • Modeling of biological membrane mimics • Force field development for different lipid types • Study of the effect of different anesthetics in molecular dynamics simulations both on the membrane and on ion channels Project 3: Pore Formation in Biological Membranes by Electric Fields and Anitibiotic Peptides Problems: • Characteristics of Membrane Pore Formation Aims: • Modeling of biological membrane mimics • Force field development for different lipid types • Effect of different antibiotic peptides and electric fields on biological membranes, peptide design Requirements: Bachelor/Master in Chemistry, Physics, or Bioinformatics, Linux experience We offer: international working environment, state-of-the-art computational resources, participation in international conferences Further information: Please contact Prof. Rainer Böckmann E-mail: rainer.boeckmann@biologie.uni-erlangen.de Phone: 0049 - 9131/85-25409 __________________________________________________________ Prof. Dr. Rainer Böckmann Computational Biology Universität Erlangen-N¨¹rnberg Staudtstr. 5 91058 Erlangen Phone: ++49 +9131 85-25409 FAX: ++49 +9131 85-25410 E-Mail: rainer.boeckmann@biologie.uni-erlangen.de http://www.biotechnik.nat.uni-erlangen.de/research/boeckmann/ [ Last edited by flyingskynk on 2012-5-18 at 23:25 ] |
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