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不孤鸟

铁虫 (初入文坛)

应助: 0 (幼儿园)
金币: 377.1
帖子: 30
在线: 14.3小时
虫号: 1189983
注册: 2011-01-14
性别: GG
专业: 泌尿系统肿瘤

[交流] 请问慢乙肝的病人敢用苯溴马隆吗

如题，病人别嘌醇0.1 bid 后尿酸仍在五百多，现在建议苯溴马隆口服，但是查了资料说赛诺菲已经在03年因为苯溴马隆的肝损召回了，没有这方面的经验，请指教。

http://apps.who.int/medicinedocs/en/d/Js4947e/1.4.html 这是WHO的关于苯溴马隆召回的材料。

BENZ-BROMARONE - Withdrawn due to reports of liver damage

France. Sanofi-Synthélabo has withdrawn its hyperuricaemic product benzbromarone (Desuric) in France following reports of serious liver damage associated with the product's use. Benzbromarone (Desuric) has been marketed in France since 1976, but rare reports of serious cytolytic liver damage, including fatal cases and others requiring liver transplants, have led to an unfavourable benefit/risk ratio. The company has therefore decided to stop the marketing of this product in France and to recall all stocks.

Reference:

Chaibriant H. Stop marketing of proprietary medical product DESURIC (Rm) (benzbromarone), 22 Apr 2003. Available from URL: http://agmed.sante.gouv.fr

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