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One-Pot Synthesis of Near-Infrared Fluorescent Gold Clusters for Cellular Fluorescence Lifetime Imaging

Li Shang, Naghmeh Azadfar, Florian Stockmar, Winfried Send, Vanessa Trouillet, Michael Bruns, Dagmar Gerthsen and G. Ulrich Nienhaus
Article first published online: 2 AUG 2011 | DOI: 10.1002/smll.201100746

Fluorescent gold nanoclusters stabilized with the bidentate ligand dihydrolipoic acid have been synthesized with a facile one-pot strategy. The prepared gold clusters possess bright near-infrared fluorescence, ultrasmall size, and good biocompatibility. Moreover, their long fluorescence lifetime makes them attractive as biolabels in fluorescence lifetime imaging applications.

Link: http://onlinelibrary.wiley.com/d ... .201100746/abstract

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