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烟云听雨铁杆木虫 (正式写手)
金虫
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[求助]
翻译一段文献（有机化学）
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In addition to the scaffold bearing the ethyl side chain of stenine and neostenine, a collection of nonnatural Stemonalike ketoamide scaffolds were constructed via this route, which then served as the substrates for the preparation of six sets of functionalized analogues. These bore core changes that could not be readily accomplished by modification of the natural product itself. Representative examples of the various pathways of these initial efforts are shown in Scheme 2. Almost exclusively, these analogues displayed ring systems or functional groups substantially different from those of the natural products, including carbamates, amides, aryl groups, and heterocyclic moieties (e.g., indole and quinoline) (39). At the outset, it was unknown whether these analogues would possess any significant binding activity. |
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8814402
至尊木虫 (职业作家)
- 翻译EPI: 509
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- 专业: 药物学其他科学问题
2楼2011-07-13 09:55:18
3楼2011-07-13 10:14:00
8814402
至尊木虫 (职业作家)
- 翻译EPI: 509
- 应助: 18 (小学生)
- 贵宾: 0.381
- 金币: 12916.1
- 散金: 47
- 红花: 16
- 帖子: 4183
- 在线: 357.8小时
- 虫号: 1184404
- 注册: 2011-01-06
- 专业: 药物学其他科学问题
【答案】应助回帖
★ ★
烟云听雨(金币+15, 翻译EPI+1): 非常感谢，翻译的很好，仰慕！能否再帮翻译？谢谢 2011-07-13 12:36:15
Mally89(金币+2): 感谢应助！~ 2011-07-18 20:09:23
烟云听雨(金币+15, 翻译EPI+1): 非常感谢，翻译的很好，仰慕！能否再帮翻译？谢谢 2011-07-13 12:36:15
Mally89(金币+2): 感谢应助！~ 2011-07-18 20:09:23
| In addition to the scaffold bearing the ethyl side chain of stenine and neostenine, a collection of nonnatural Stemonalike ketoamide scaffolds were constructed via this route, which then served as the substrates for the preparation of six sets of functionalized analogues. 除了带有斯替宁碱和新斯替宁碱的乙烷基侧链的支架，一系列非天然百部样氨基酮支架通过这一路线构建。These bore core changes that could not be readily accomplished by modification of the natural product itself. 这产生的核心变化不易于通过对天然产物自身的修饰而实现。Representative examples of the various pathways of these initial efforts are shown in Scheme 2. 这些开创性努力的不同路径的代表性例子显示于示意图2中。Almost exclusively, these analogues displayed ring systems or functional groups substantially different from those of the natural products, including carbamates, amides, aryl groups, and heterocyclic moieties (e.g., indole and quinoline) (39). 几乎是无一例外的，这些类似物都显示了与天然产物相当不同的环系统和官能团，包括氨基甲酸、酰胺、芳基集团和局部杂环结构（如吲哚和喹啉）。At the outset, it was unknown whether these analogues would possess any significant binding activity.起初，这些类似物是否具有有效的结合活性尚不得而知。 |
4楼2011-07-13 10:20:27
