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We found that specific and intermediate compounds, regardless of source, are well-distributed throughout the space, whereas promiscuous compounds are significantly concentrated in the center (p < 0.0099). Because the center of the space corresponds to common property filters, this result suggests that our binding experiments accessed a greater number of desirable outcomes (specific binding) than had we restricted ourselves to compounds passing common filters. |
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huqionghhkk(½ð±Ò+10): 2011-07-08 23:27:51
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