|
|
【答案】应助回帖
★
lgq101(金币+15, 翻译EPI+1): 谢谢~~~~~ 2011-06-24 12:16:53
Mally89(金币+1): 感谢应助！~ 2011-06-24 21:36:36
Tanaka et al.’s Ru(I)-catalyzed [2 + 2 + 2] cyclotrimerization of ethyl cyanoformate (28, 29) also proceeded effectively for diynes 4a,b,d, to afford pyrrolopyridine carboxylates 28a,b,d regioselectively. Tanaka等的氰甲酸乙酯钌催化[2 + 2 + 2]环三聚反应也可高效地以二炔4a、b、d为底物进行并提供区域选择性。Deiters and coworkers have carried out similar reactions previously on solid support (27, 30). Deiters及其同事先前在固相载体上进行了相似的反应。
Similarly, Saito and coworkers’ Ni(0)-catalyzed [3 + 2 + 2] cycloaddition with ethyl cyclopropylidene acetate (31) was translated effectively to solid support-bound diynes 4a–c. 与上述类似，Saito及其同事的ethyl cyclopropylidene acetate 镍催化[3 + 2 + 2] 环化加成也被有效地引入到二炔4a-c为底物的的固相载体合成中。 The initial cycloheptapyrrolidine ester products were then converted to the corresponding Weinreb amides 29a–c/29′a–c (32) to facilitate downstream separation of E and Z isomers after cleavage from the solid support.最初的cycloheptapyrrolidine ester产物随后被转化为相应的Weinreb酰胺29a–c/29′a–c，以利于E和Z同分异构体从载体上解离下来后的下游分离。 |
|
回复此楼
10+3