| 查看: 346 | 回复: 1 | |||
lgq101木虫 (小有名气)
|
[求助]
求翻译~~~谢谢【有机合成】
|
|
Indeed, we were delighted to find that translation to solid phase proved largely uneventful for the majority of these reactions. Consistent with our solution-phase results, Krische and coworkers’ Rh(I)–2,2′-bis(diphenylphosphino)-1,1′-binaphthyl (BINAP) catalyzed reductive cyclization (21) proceeded with reagent-controlled diastereoselectivity for 3a,b, but not for 3d, affording access to both exo-pyrroline relative diastereomers 6a,b and 6′a,b and the major diastereomer 6d (Scheme 2). The yields and diastereoselectivities were comparable to those observed in the original solution-phase studies in this first application to solid-phase synthesis. Enynes 3a,b,d also underwent Evans et al.’s diastereoselective Rh(I)-catalyzed [4 + 2 + 2] reaction with 1,3-butadiene successfully successfully (22). This reaction has not previously been used in solidphase synthesis and, based on our previous solution-phase studies, the sulfinamides were oxidized to the corresponding sulfonamides prior to cycloaddition, leading to cyclooctapyrrolidines 7a,b,d. [ Last edited by Mally89 on 2011-6-17 at 20:52 ] |
回复此楼» 猜你喜欢
售SCI一区文章，我:8O5.5.1.O5.4,科目全,可伽急
已经有3人回复
-
售SCI一区文章，我:8.O.551.O.5.4,科目全,可伽急
已经有3人回复
-
售SCI一区T0P文章，我:8O.55.1.O.5.4,科目齐全,可+急
已经有3人回复
-
售SCI文章，我:8O5.5.1.O.54,科目齐全,可+急
已经有3人回复
-
售SCI一区文章，我:8.O.551.O.5.4,科目全,可伽急
已经有3人回复
-
售SCI文章，我:8O5.5.1.O.54,科目齐全,可+急
已经有3人回复
-
售SCI-T0P文章，我:8O.5.5.1.O.54,科目齐全,可+急
已经有6人回复
-
售一区SCI文章T0P，我:8O.551.O54,科目全,可十急
已经有9人回复
-
售SCI-T0P文章，我:8O.5.5.1.O.54,科目齐全,可+急
已经有3人回复
-
考博求助
已经有3人回复
lgq101
木虫 (小有名气)
- 应助: 1 (幼儿园)
- 金币: 1767.6
- 红花: 1
- 帖子: 167
- 在线: 23.3小时
- 虫号: 1158383
- 注册: 2010-11-29
- 性别: GG
- 专业: 天然有机化学
2楼2011-06-14 12:48:56
