| 查看: 280 | 回复: 0 | ||
huqionghhkk木虫 (小有名气)
|
[求助]
翻译一段（药物化学）谢谢！
|
|
We recently analyzed a large compound collection in 100 parallel protein-binding assays (48) and found both proteinbinding frequencies and specificities are increased among compounds having intermediate stereochemical complexity. Here,we extend analysis of the same compounds to physicochemical properties (6, 7, 16, 54) and shape-based descriptors (27, 29), revealing additional similarities and differences between sets. We use principal component analysis (PCA) (55) of chemically intuitive properties to analyze sources of variation among the sets. Different descriptors report different aspects of chemical structure (36), and we aim to illustrate for synthetic chemists how quantitative relationships can be reconciled with chemical intuition. |
回复此楼» 猜你喜欢
293调剂
已经有3人回复
-
机械工程264学硕求调剂
已经有3人回复
-
264求调剂
已经有9人回复
-
求调剂
已经有6人回复
-
22408 266求调剂
已经有7人回复
-
求调剂
已经有14人回复
-
273求调剂
已经有43人回复
-
307求调剂
已经有13人回复
-
327求调剂
已经有7人回复
-
338求调剂
已经有6人回复
