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至尊木虫 (职业作家)

翻译EPI: 509
应助: 18 (小学生)
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虫号: 1184404
注册: 2011-01-06
专业: 药物学其他科学问题

【答案】应助回帖

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sltmac(金币+2): 谢谢应助~~ 2011-05-31 15:23:37
落迦(金币+10, 翻译EPI+1): 谢谢关注 2011-05-31 19:52:20

The topic of sex differences in adverse responses to drugs is gaining much attention at the moment, as data in regards to gender dimorphic toxicity in the clinic are rapidly emerging [4,5]. 当有关性别二态性毒性现象在临床快速出现时，对在药物不良反应中的性别差异话题渐渐引起了更多的注意。Much of these data rule out some obvious gender differences (such as body weight and body fat) [6,7] as major causal factors. 这些资料中的大多数都将某些明显的性别差异（诸如体重和脂肪含量）作为主要起因。However, it is possible that hormonal signaling underlies these basic differences which are poorly understood at the moment. 然而，激素信号是这些基础差异的基础，可能这些事实在那时还认识不足。 Hence, there is a compelling need for basic research at the molecular level, in order to comprehend and thus perhaps prevent these sex differences in adverse responses in the future.因此，急需在分子水平进行基础研究，以理解和在将来防止药物不良反应中的性别差异。

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