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[交流] 2005 Wiley eBook:Metabolism by In Vivo NMR: The Goal of Proteomics

Title: Metabolism by In Vivo NMR: The Goal of Proteomics
Author: Robert G. Shulman (Editor), Douglas L. Rothman
Publisher: Wiley
Publication Date: 2005-02-07
Number Of Pages: 206
http://www.amazon.com/exec/obidos/ASIN/0470847190/ebooksclub-20/
Book Description
Metabolism By In Vivo NMR reviews and extends the experimental and theoretical reports concerning in vivo NMR, a pioneering approach that offers versatile new ways of studying metabolic pathways. Perfectly timed to coincide with recent findings that demonstrate the novelty and strength of this approach, the book covers recent applications in biochemistry, medicine, and psychology; in vivo NMR techniques; MCA; glucose metabolism focusing on glycogen; the value of muscle glycogen measurements in exercise; and much more.

* This book is unique in linking in vivo 13C NMR measurements of neuronal activity and energetics with applications to functional imaging and certain disease states
* Provides a fundamental neurochemical explanation of brain activity applicable to functional imaging, theories of neuronal activity and disease states, e.g. epilepsy, psychiatric diseases and developmental disorders
* Novel and potentially controversial
* Will inspire future research directions.

Download Description
This book is unique in linking in vivo 13 C NMR measurements of neuronal activity and energetics with applications to functional imaging and certain disease states. Provides a fundamental neurochemical explanation of brain activity applicable to functional imaging, theories of neuronal activity and disease states, e.g. epilepsy, psychiatric diseases and developmental disorders Novel and potentially controversial Will inspire future research directions .

Table of Contents
SECTION A: Background.
1 Introduction
2 In Vivo NMR Spectroscopy Techniques; Direct Detection; MRS; Kinetics and Labels; Fluxes; Concentrations
3 Metabolic Control Analysis for the NMR Spectroscopist
SECTION B: 13C and 31P NMR Studies of the Regulation of Glucose Metabolism.
4 MRS Studies of the Role of the Muscle Glycogen Synthesis Pathway in the Pathophysiology of Type 2 Diabetes .
5 Phosphorylation of Allosteric Enzymes can serve Homeostasis rather than Control Flux: the Example of Glycogen Synthase
6 Regulation of Glycogen Metabolism in Muscle during Exercise .
7 13C NMR Studies of Heart Glycogen Metabolism .
8 Bioenergetics Implication of Metabolic Fluctuation during Muscle Contraction .
9 Lactate, Glycogen and Fatigue .
10 Futile Cycling in Yeast: How to Control Gluttony in the Midst of Plenty
11 Trehalose Energetics in Yeast Spores .
12 Metabolic Networks in the Liver by 2H and 13C NMR
13 Summarized Reflections on Metabolism
Index.
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