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Therefore, for any fixed volume of maternal plasma, the number of quantifiable sequences would be much greater than the number of DNA molecules that could serve as templates for detection by gene locus-specific assays. Hence, precise detection of the over- or underrepresentation of sequences from an aneuploid chromosome could be more readily achieved.

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lihuanzheng(金币+5, 翻译EPI+1): 2011-03-16 17:47:51
Therefore, for any fixed volume of maternal plasma, the number of quantifiable sequences would be much greater than the number of DNA molecules that could serve as templates for detection by gene locus-specific assays. Hence, precise detection of the over- or underrepresentation of sequences from an aneuploid chromosome could be more readily achieved.

因此,对于任何一定量的孕妇血浆,由于量化序列的数目比DNA分子的数目要大,所以(量化序列)可以作为基因特异性位点分析检测的模板。由此,在非整倍体染色体中进行过度表达或表达不足序列的精确检测会更容易实现。
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