| 查看: 884 | 回复: 4 | |||
[交流]
求翻译
|
|
标题是:Stress Degradation Studies on Aripiprazole and Development of a Validated Stability Indicating LC Method 内容是: The present paper describes the development of a stability indicating reversed phase column liquid chromatographic method for aripiprazole in the presence of its impurities and deg- radation products generated from forced decomposition studies. The drug substance was subjected to stress conditions of aqueous hydrolysis, oxidative, photolytic and thermal stress degradation. The degradation of aripiprazole was observed under acid hydrolysis and peroxide. The drug was found to be stable to other stress conditions attempted. Successful separation of the drug from the synthetic impurities and degradation products formed under stress conditions was achieved on an Inertsil phenyl column using a mixture of 0.2% triflu- oroacetic acid and acetonitrile (55:45, v/v). The developed LC method was validated with respect to linearity, accuracy, precision, specificity and robustness. The assay method was found linear in the range of 25–200 lgmL -1 with a correlation coefficient of 0.9999 and the linearity of the impurities were established from LOQ to 0.3%. Recoveries of the assay and impurities were found between 97.2 and 104.6%. The developed LC method for the related substances and assay determination of aripiprazole can be used to evaluate the quality of regular production samples. It can also be used to test the stability samples of aripiprazole. To the best of our knowledge, the validated stability indicating LC method which separates all the impurities disclosed in this investigation was not published elsewhere. |
» 猜你喜欢
售SCI一区文章,我:8.O.551.O.5.4,科目全,可伽急
已经有8人回复
售SCI一区T0P文章,我:8O.55.1.O.5.4,科目齐全,可+急
已经有8人回复
售SCI一区文章,我:8.O.551.O.5.4,科目全,可伽急
已经有9人回复
找导师
已经有8人回复
售SCI-T0P文章,我:8O.5.5.1.O.54,科目齐全,可+急
已经有5人回复
售SCI一区T0P文章,我:8.O55.1.O.54,科目全,可十急
已经有9人回复
面上没中,邀请各位路过的虫友分析一下分数
已经有3人回复
售一区SCI文章T0P,我:8O.551.O54,科目全,可十急
已经有8人回复
售SCI一区T0P文章,我:8O.55.1.O.54,科目全,可伽急
已经有11人回复
售SCI一区文章,我:8.O.551.O.5.4,科目全,可伽急
已经有6人回复
» 抢金币啦!回帖就可以得到:
云南大学丁军桥团队2027年博士招生
+1/805
南京大学医学院附属鼓楼医院 肿瘤疫苗与纳米医学团队 博士后招聘
+1/92
山东大学晶体材料全国重点实验室招收2027年锂金属电池负极材料博士一名
+1/90
江西理工大学稀土学院博士招聘(安家费启动金等合计超100w)
+1/90
课题组招推免硕士和直博生。华中科技大学光电学院发光材料与器件团队。
+1/87
2027级博士研究生——质谱分析
+5/85
武汉大学高等研究院超分子化学与材料课题组2027级招收硕士和博士研究生及研究助理
+1/84
复旦大学芯片与系统前沿技术研究院 朱忠赟珅 课题组招收2027级博士研究生
+1/78
以色列理工-生物质、塑料等催化转化2-3名---全奖博士研究生(随时入学)和科研助理
+1/22
评职称需要,卖发明专利了:D有技术储备需求的设备厂商可联系
+1/18
新加坡国立大学Sibudjing Kawi教授课题组招聘博士后(热催化/等离子体催化方向)
+1/10
北京科技大学能源与环境工程学院 博士、博士后招聘启事
+1/7
石蜡切片VS冰冻切片:哪种更适合免疫荧光检测?
+1/7
新加坡国立大学Sibudjing Kawi教授课题组part-time PhD(热催化/等离子体催化方向)
+1/7
【科研诚信】武汉轻工大学何江玲3篇论文:涉嫌抄袭、成组数据重复、制造虚假显著
+1/3
上海交通大学纳米光子学实验室招收直博生(2027级)
+1/3
义翘神州推出全长p-Tau217蛋白,助力阿尔茨海默病下一代生物标志物检测开发
+1/2
结肠炎多维度分子解析:炎症‑免疫‑肠道屏障一体化检测策略
+1/1
香港大学先进制造实验室招收(机械类/机电一体化等专业)27年度博士和硕士研究生
+1/1
中国地质大学(北京)人工智能、电子信息方向招收博士硕士研究生(长期有效)
+1/1
2楼2010-12-08 15:55:12
3楼2010-12-09 13:57:18
4楼2010-12-09 16:46:47
★ ★
ringzhu(金币+2):哈哈~~偶也觉得他那句话说的很不错 可以拿来放在版规里边~~ 2010-12-16 10:29:57
ringzhu(金币+2):哈哈~~偶也觉得他那句话说的很不错 可以拿来放在版规里边~~ 2010-12-16 10:29:57
| 唉……楼主应该自强不息啊,做学问的,基本上英文都问题不大,实在不行,也可以翻着字典一点一点来。论坛上有求助翻译的也就一小段或者几句话,或者是自己根本不掌握的语种……楼主这种情况,实在应该反省自身。——————————————————————————————————————转自pulllantern 金虫 原帖见https://muchong.com/bbs/viewthread.php?tid=2676686&fpage=1 |
5楼2010-12-14 20:44:06










回复此楼