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Clinical Manifestations of Spinal DISH
Clinical symptoms in spinal DISH are usually mild and
include spinal stiffness and mild intermittent and nonradiating
thoracolumbar pain that becomes evident in middle
age. Generally, no significant change occurs in normal spinal
mechanics, and the clinical findings are usually mild in
comparison with the extent of the radiographic abnormalities.
With progression of the disease, pain and stiffness may
involve the lumbar and cervical segments [2]. Occasionally,
patients with DISH may have severe limitation of spinal
mobility and associated postural abnormality as is seen
with advanced ankylosing spondylitis [7]. Prominent flowing
ossifications of DISH in the cervical spine can cause
dysphagia [2, 4, 8]. However, many patients with DISH are
asymptomatic and their disease is discovered incidentally
[4]. The association of ossification of the posterior longitudinal
ligament (OPLL) and ossification of the ligamentum
flavum with DISH may explain, in part, the occasional
presence of neurologic findings in patients with DISH [2,
9]. Sharma et al. [10] showed in retrospective analysis that
15% of patients with DISH presenting to a particular neurosurgical
unit had serious neurologic manifestations requiring
neurosurgical intervention.

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