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The incorporation of PZQ in small unilamellar liposomes composed of PC can allow the drug administration in an aqueous media without decreasing the effect of S. mansoni of the drug, since it is related with the lipophilic profile of the drug due to the interaction between the drug and the parasite membrane. The incorporation of PZQ in liposomes showed similar effect of the effect on S. mansoni cultures. 主要是后半句 [ Last edited by 23010402 on 2010-8-28 at 20:36 ] |
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