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¡¡¡¡ÎÄÕ±àºÅ£º1009-4237(2000)03-0150-03


Observation of fetal cartilage wound healing


hUANG Wei,LIU Da-lie,GUI Xing-hua(Department of Plastic Surgery, General Hospital of Shenyang Military Region, Shenyang 110015)


¡¡¡¡Abstract£ºObjective To detremine whether fetal cartilage shares the unique scarless healing properties of fetal skin. Methods Full thickness in cisional ear wounds were created and sutured in fetal rabbits at 23 days' gestation(full term, 31 days')and in adult control rabbits. We harvested the samples of fetal rabbits at days 3,5,7,14 post wounding and the samples of adult rabbits at days 3,7,14,21 post wounding. Assessment at that time included evaluation of gross morphology, histologic and electronic microscopic appearance. Results Both fetal and adult cartilage wounds healed with scar formation. In contrast to adult wounds, no significant inflammatory response was foundd in fetal sounds. Conclusion Fetal cartilage healed more rapidly and without significant inflammation.


¡¡¡¡Keywords£ºfetal; cartilage; wound healing²Î¿¼ÎÄÏ×£º


¡¡¡¡£Û1£ÝLongaker MT£¬Dodson TB£®A rabbit model for fetal cleft lip repair[J]. J Oral Maxillo Face Surg£¬1990£¬48(7)£º714-719


¡¡¡¡£Û2£ÝLongaker MT£®Studies in fetal wound healing£ºV£®Second and early third ttrimester fetal wounds demonstrate rapid collagen deposition without scar formation[J]£®J Pediatr Surg£¬1990£¬25£º63£®


¡¡¡¡£Û3£ÝGoss AN£®Intra-uterine healing of fetal rat oral mucosal skin and cartilage wounds[J]£®J Oral Pathol£¬1977£¬6(1)£º35-43
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