24СʱÈÈÃŰæ¿éÅÅÐаñ    

²é¿´: 814  |  »Ø¸´: 5

ÀÇÀÇǬÀ¤

Ìú¸Ëľ³æ (Ö°Òµ×÷¼Ò)

[½»Á÷] ¡¾ÇóÖú/½»Á÷¡¿ÕâÊÇʲôÎÄÏ×£¿

Biomedicine:
Adding ZPP to Cancer Detection

Paula A. Kiberstis
Like many other cancers, prostate cancer is more responsive to therapy when it is diagnosed at an early stage. Blood tests for PSA (prostate-specific antigen), a cancer screening strategy introduced over two decades ago, have led to a significant reduction in death rates from the disease. The PSA test is imperfect, however, because it fails to distinguish cancer from some benign conditions of the prostate and hence can lead to overdiagnosis and overtreatment. Researchers have continued to search for more sensitive and specific markers for detecting and monitoring the disease.

Ghosh et al. have begun to explore whether the solution might be as simple as monitoring the zinc content of prostate tissue. Healthy prostate tissue contains high levels of mobile zinc, but these levels fall dramatically when malignant (but not benign) growth occurs. By combining a zinc-specific fluorescent probe, ZPP1, with optical imaging approaches, the authors found that they could detect and follow noninvasively the progression of prostate cancer in mice by monitoring zinc loss in prostate tissue over time. The authors speculate that once optical imaging approaches are adapted for clinical use, this zinc test could potentially be developed into a sensitive and specific tool for human prostate cancer detection.

Cancer Res. 70, 6119 (2010).

ÀϰåÈÃÎÒÏÂÔØµÄÎÄÏ×£¬ÏÂÃæµÄÆÚ¿¯¾íºÅºÍÎÄÕÂÌâÄ¿×÷Õß²»Ò»Ö£¿£¿£¿£¿ÕæÔΰ¡£¡Çó¸ßÈËÖ¸½ÌÕâÊÇÕ¦»ØÊÂ
»Ø¸´´ËÂ¥

» ²ÂÄãϲ»¶

» ±¾Ö÷ÌâÏà¹Ø¼ÛÖµÌùÍÆ¼ö£¬¶ÔÄúͬÑùÓаïÖú:

ŬÁ¦ÕÒ·½Ïò£¡
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

jiarui5582

½ð³æ (ÖøÃûдÊÖ)

ûÃ÷°×ÄãµÄÎÊÌ⣬ûÓÐʲô²»Ò»Ö°¡£¿
ÓÐЩ·Äã±ØÐë×ߣ¬¼´Ê¹Äã²»ÇéÔ¸£¡
2Â¥2010-08-23 15:04:23
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

ÀÇÀÇǬÀ¤

Ìú¸Ëľ³æ (Ö°Òµ×÷¼Ò)

ÒýÓûØÌû:
Originally posted by jiarui5582 at 2010-08-23 15:04:23:
ûÃ÷°×ÄãµÄÎÊÌ⣬ûÓÐʲô²»Ò»Ö°¡£¿

ÌâÄ¿×÷ÕßÓëÎÄÏ×¾íºÅËùʾµÄÎÄÏײ»Ò»ÖÂ
ŬÁ¦ÕÒ·½Ïò£¡
3Â¥2010-08-23 16:56:10
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

xp198766

Ìú¸Ëľ³æ (ÖøÃûдÊÖ)

Сľ³æÖ°Òµ´ò½´Ó͵Î~~£¡

ÎÒ¾õµÃ¿ÉÒÔ¶¼¿´Ò»¿´Â¿ÉÄÜÊÇÀϰå¸ã´íÁËÄØ£¬ºÇºÇ
4Â¥2010-08-23 17:16:06
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

ÀÇÀÇǬÀ¤

Ìú¸Ëľ³æ (Ö°Òµ×÷¼Ò)

ÒýÓûØÌû:
Originally posted by xp198766 at 2010-08-23 17:16:06:
ÎÒ¾õµÃ¿ÉÒÔ¶¼¿´Ò»¿´Â¿ÉÄÜÊÇÀϰå¸ã´íÁËÄØ£¬ºÇºÇ

ÀϰåÈÃÎÒ¸øËûÏÂÔØ
ŬÁ¦ÕÒ·½Ïò£¡
5Â¥2010-08-23 19:31:11
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû

xp198766

Ìú¸Ëľ³æ (ÖøÃûдÊÖ)

Сľ³æÖ°Òµ´ò½´Ó͵Î~~£¡

ÀÇÀÇǬÀ¤(½ð±Ò+5):ÎÒÒ²¾õµÃÊÇÁ½Æª 2010-08-23 20:49:46
http://cancerres.aacrjournals.org/content/70/15/6119.abstract
Ó¦¸ÃÊÇÁ½Æª£¬ÕâÊǺóÃæÒ»Æª£¬Ç°ÃæÒ»ÆªÃ»ÕÒµ½£¬Äã×Ô¼º²éһϰÉ
6Â¥2010-08-23 20:20:40
ÒÑÔÄ   »Ø¸´´ËÂ¥   ¹Ø×¢TA ¸øTA·¢ÏûÏ¢ ËÍTAºì»¨ TAµÄ»ØÌû
Ïà¹Ø°æ¿éÌø×ª ÎÒÒª¶©ÔÄÂ¥Ö÷ ÀÇÀÇǬÀ¤ µÄÖ÷Ìâ¸üÐÂ
×î¾ßÈËÆøÈÈÌûÍÆ¼ö [²é¿´È«²¿] ×÷Õß »Ø/¿´ ×îºó·¢±í
[¿¼ÑÐ] 08¹¤Ñ§µ÷¼Á +12 Óû§573181 2026-03-20 17/850 2026-03-24 21:45 by ·¬ÇÑìÀÁËÎ÷ºìÊÁ
[¿¼ÑÐ] ²ÄÁÏר˶ÕÒµ÷¼Á +5 ¹þ¹þ¹þºðºðºð¹þ 2026-03-23 5/250 2026-03-24 19:07 by ÁËÁËÁËÁË¡£¡£
[¿¼ÑÐ] 274Çóµ÷¼Á +5 ¹Ë¾ÅóÏҪǫÐé 2026-03-24 5/250 2026-03-24 18:43 by jhhcooi
[¿¼ÑÐ] ×ÊÔ´Óë»·¾³ µ÷¼ÁÉêÇë(333·Ö) +7 holy J 2026-03-21 7/350 2026-03-24 17:24 by xiaohai104
[¿¼ÑÐ] 306Çó0703µ÷¼ÁÒ»Ö¾Ô¸»ªÖÐʦ·¶ +10 Ö½Óãly 2026-03-21 11/550 2026-03-24 17:22 by qingfeng258
[¿¼ÑÐ] 321Çóµ÷¼Á +4 Ymlll 2026-03-24 4/200 2026-03-24 14:44 by sprinining
[¿¼ÑÐ] 293Çóµ÷¼Á +6 ¼ÓÒ»Ò»¾Å 2026-03-24 6/300 2026-03-24 14:29 by JourneyLucky
[¿¼ÑÐ] Ò»Ö¾Ô¸¹þ¹¤´ó£¬085400£¬320£¬Çóµ÷¼Á +3 gdlf9999 2026-03-24 3/150 2026-03-24 10:08 by ²«»÷518
[»ù½ðÉêÇë] Çë½ÌÏ´ó¼Ò 2026Äê¹ú¼Ò»ù½ðÉêÇëÊÇ˫äÉóÂ𣿠+3 lishucheng1 2026-03-22 5/250 2026-03-24 08:22 by gltch
[¿¼ÑÐ] Çóµ÷¼Á +7 Ê®Èý¼ÓÓÍ 2026-03-21 7/350 2026-03-23 23:48 by ÈÈÇéɳĮ
[¿¼ÑÐ] ÉúÎïѧһ־Ը985£¬·ÖÊý349Çóµ÷¼Á +6 zxts12 2026-03-21 9/450 2026-03-23 18:37 by macy2011
[¿¼ÑÐ] 336»¯¹¤µ÷¼Á +4 Íõ´ó̹1 2026-03-23 5/250 2026-03-23 18:32 by allen-yin
[¿¼ÑÐ] Ò»Ö¾Ô¸ÉϺ£½»´óÉúÎïÓëҽҩר˶324·Ö£¬Çóµ÷¼Á +5 jiajunX 2026-03-22 5/250 2026-03-23 18:07 by YMUÊ©ÀÏʦ
[¿¼ÑÐ] ѰÕÒµ÷¼Á +4 ¾óǿâ? 2026-03-21 4/200 2026-03-22 16:14 by ľÍÐζ¶
[¿¼ÑÐ] 311Çóµ÷¼Á +3 26ÑÐ0 2026-03-20 3/150 2026-03-22 14:46 by ColorlessPI
[¿¼ÑÐ] 286Çóµ÷¼Á +10 Faune 2026-03-21 10/500 2026-03-21 23:34 by 314126402
[¿¼ÑÐ] ²ÄÁÏѧ˶301·ÖÇóµ÷¼Á +7 Liyouyumairs 2026-03-21 7/350 2026-03-21 22:31 by peike
[¿¼ÑÐ] ¿¼Ñе÷¼Á +3 ºôºô£¿~+123456 2026-03-21 3/150 2026-03-21 20:04 by Î޼ʵIJÝÔ­
[»ù½ðÉêÇë] ѧУÒѾ­Ìá½»µ½NSFC£¬»¹ÄÜÐÞ¸ÄÂ𣿠40+4 babangida 2026-03-19 9/450 2026-03-21 16:12 by babangida
[¿¼ÑÐ] ²ÄÁÏѧѧ˶080502 337Çóµ÷¼Á-Ò»Ö¾Ô¸»ªÖпƼ¼´óѧ +4 ˳˳˳mr 2026-03-18 5/250 2026-03-21 10:22 by luoyongfeng
ÐÅÏ¢Ìáʾ
ÇëÌî´¦ÀíÒâ¼û