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These results seem to be due to the introduction of a new anchor point, which is formed by a new hydrogen bond between the C=O of C2 side chain of 4b6 and NNBPY.

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Any structural modifications affecting the formation of hydrogen bond at C4- C=O moiety of the pyrimidine ring can result in compounds devoid of activity.

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zerohead

½û³æ (Ö°Òµ×÷¼Ò)

î£ÃùÓã(½ð±Ò+4, ·­ÒëEPI+1):3Q 2010-08-14 23:05:34
These results seem to be due to the introduction of a new anchor point, which is formed by a new hydrogen bond between the C=O of C2 side chain of 4b6 and NNBPY.
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Such results may due to the introduction of a new anchor point, which is formed by the new hydrogen bond generated between NNBPY and the C=O at the C2 side chain of 4b6.
3Â¥2010-08-14 22:05:01
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cfk580713

ÖÁ×ðľ³æ (ÖøÃûдÊÖ)

î£ÃùÓã(½ð±Ò+1): 2010-08-14 23:05:57
These results seem to result from the introduction of a new anchor point at the C=O of C2 side chains, which is formed by a new hydrogen bond between 4b6 and NNBPY.

Any structural modifications affecting the formation of hydrogen bond at C4- C=O moiety of the pyrimidine ring could result in activity devoid of the compounds.

±¾ÎÄÀ´×Ô: Сľ³æÂÛ̳ https://muchong.com/bbs/viewthread.php?tid=2299656&fpage=1
2Â¥2010-08-14 20:49:09
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