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【求助】关于动物模型的两个问题 已有1人参与
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提问一:请问有谁知道HMA动物模型是什么动物模型吗?英文全称是(human microbiota-associated (HMA) animals. 提问二:monoassociated animal models 是什么动物模型? 谢谢,希望能够详细点! |
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HMA rats Animal experiments were approved and carried out under the supervision of the Danish National Agency for Protection of Experimental Animals. Three germfree Sprague–Dawley rats, aged 8 weeks, were used. Rats were bred at the National Food Institute from parental animals originally obtained from Taconic. Animals were dosed orally with 1 mL of human faecal suspension, kept in isolators as described previously (Schlundt et al., 1994), and fed with -irradiated Altromin 1314 (Brogaarden, Denmark). Samples were taken by provoked defaecation 2 weeks after dosage with human microbiota and maintained at ?20 °C until use. |

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