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½£ÇÅÉúÎﻯѧÓë·Ö×ÓÉúÎïѧ´Çµä Oxford Dictionary of Biochemistry and Molecular Biology

It is a decade since the first edition of the Oxford Dictionary of Biochemistry and Molecular Biology. It was a remarkable work of scholarship, arising from the work of journal editors and scientific writers. Since then the landscape of biochemistry has changed immeasurably. The genome sequences have laid out the blueprints of whole organisms, especially Man. They have revealed the diversity of gene expression, and the complex systems by which cellular molecules organize themselves. The molecular basis of many diseases has been revealed, and vital cellular components discovered.

The literature is more diverse than ten years ago. The identification of the genes has rushed ahead of the biochemical characterization of their functions. Many protein and nucleic acid factors have been discovered. While their functions are incompletely understood, they are referred to by laboratory shorthand abbreviations. These are well understood by the investigators who work on them, but the mass of them becomes very confusing to the student, or to those viewing biochemistry from the outside. New methods of bioinformatics have been developed to bridge the gap. Meanwhile the ¡®-omics¡¯ projects have introduced new layers of complexity as we see the interactions between macromolecules leading to new emergent properties.

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