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[求助]
【求租2】修改一段英文。。。咋没有人帮忙啊，bb提高30枚
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The world wide ageing of the population has increased the incidence of cognitive deficits, such as the age-associated memory impairment and senile dementias and Alzheimer’s disease [1]. Extensive evidence supports the view that cholinergic mechanisms modulate learning and memory formation [2]. Acetylcholinesterase (AChE), a key enzyme in cholinergic transmission in the nervous system, is remarkably efficient in hydrolyzing acetylcholine (ACh) into acetate and choline and functions at cholinergic synapses by terminating chemical impulse of the neurotransmitter ACh [3]. Inhibitors of AChE have been extensively used to increase endogenous ACh levels and thus overcome cognitive deficits [4]. Flammulina velutipes was reported to be beneficial to human memory, and FVP has been proved to improve learning and memory ability of scopolamine hydrobromid induced model mice and rats evaluated by step-through test and Morris water test [5]. However, effect of FVP on AChE activity has not been studied. In addition, some researches suggested that polysaccharides can induce cognitive improvement owing to its antioxidant activity [6]. Therefore, for any agent which can be used against cognitive deficit, it is very advantageous to have both AChE inhibitory effect accompanied with antioxidant activity. [ Last edited by 伊人笑 on 2010-7-12 at 09:00 ] |
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hust_gaoyi
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发芽土豆(金币+1):谢谢参与 2010-07-12 21:17:56
发芽土豆(金币+1):谢谢参与 2010-07-12 21:17:56
| The world wide population ageing has increased the incidence of cognitive deficits, such as the age-associated memory impairment and senile dementias and Alzheimer’s disease [1]. Extensive evidences have demonstrated cholinergic mechanisms modulate learning and memory formation [2]. Acetylcholinesterase (AChE), a key enzyme in cholinergic transmission in the nervous system, is remarkably efficient in hydrolyzing acetylcholine (ACh) into acetate and choline and functions at cholinergic synapses by terminating chemical impulse of the neurotransmitter ACh [3]. Inhibitors of AChE have been extensively used to increase endogenous ACh levels and thus overcome cognitive deficits [4]. It is reported Flammulina velutipes is beneficial to human memory and FVP has been also proved to improve learning and memory ability of scopolamine hydrobromid induced model mice and rats evaluated by step-through test and Morris water test [5]. However, effect of FVP on AChE activity has not yet been studied. Besides, it is suggested that polysaccharides can induce cognitive improvement owing to its antioxidant activity [6]. Therefore, for any agent that can be used against cognitive deficit, it is very advantageous to have both AChE inhibitory effect as well as antioxidant activity. |
2楼2010-07-12 11:52:07
zerohead
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发芽土豆(金币+1):谢谢参与 2010-07-12 21:18:02
发芽土豆(金币+1):谢谢参与 2010-07-12 21:18:02
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伊人笑, you know it is quite different to translate a whole section from only a few sentences. For one or two sentences, it could be relatively easy as one doesn't need to consider the consistence, transition, and style of writing, not mention the efficiency of telling what you want to say. So for your own case (and most of the other cases I believe), transition is a major problem. For example, the first 3 sentences can be shorted as follows: 1. The cases of cognitive deficits are increased. 2. Cholinergic mechanisms is good for the brain. 3. AChE is good for cholinergic synapse. So what are the relationships amount that 3 sentences and where are the transitions? They are basically independent and not good for reading. That may be the reason of why you are coming here and asking for help. But that’s not fair for others to do those I would call the fundamental jobs of yours. Well you may say: “Hey, why don’t you just do something meaningful instead of xy@#z.” OK, I rewrite the last sentence for you. Therefore, for any (what) agent possessing both AChE inhibitory effect and antioxidant activity, it could be used against cognitive deficit with a promising efficiency. |
3楼2010-07-12 20:30:41
IASCC
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发芽土豆(金币+1):谢谢参与 2010-07-14 17:35:06
发芽土豆(金币+1):谢谢参与 2010-07-14 17:35:06
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Just for the grammer. The worldwide ageing of the population has increased the incidence of cognitive deficits, such as the age-associated memory impairment and senile dementias and Alzheimer’s disease [1]. Extensive evidences support the view that cholinergic mechanisms modulate the ablity of learning and memory[2]. Acetylcholinesterase (AChE), a key enzyme in cholinergic transmission in the nervous system, is remarkably efficient in hydrolyzing acetylcholine (ACh) into acetate and choline and functions at cholinergic synapses by terminating chemical impulse of the neurotransmitter ACh [3]. Inhibitors of AChE have been extensively used to increase endogenous ACh levels in order to overcome cognitive deficits [4]. Flammulina velutipes were reported to be beneficial to human memory, and FVP has been proved to improve learning and memory ability of scopolamine hydrobromid induced model mice and rats evaluated by step-through test and Morris water test [5]. However, the effect of FVP on AChE activity has not been studied. In addition, some researches suggested that polysaccharides can induce cognitive improvement owing to its antioxidant activity [6]. Therefore, for any agent against cognitive deficit, it is very advantageous to have both AChE inhibitory effect and antioxidant activity. |
4楼2010-07-14 16:27:59
