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beidong6938

[交流] 帮忙翻一个摘要(生命科学)

We report here the genome sequence of an ancient human. Obtained from,4,000-year-old permafrost-preserved hair, the genome represents a male individual from the first known culture to settle in Greenland. Sequenced to an average depth of
203, we recover 79% of the diploid genome, an amount close to the practical limit of current sequencing technologies. We identify 353,151 high-confidence single-nucleotide polymorphisms (SNPs), of which 6.8% have not been reported previously. We estimate raw read contamination to be no higher than 0.8%. We use functional SNP assessment to assign possible phenotypic characteristics of the individual that belonged to a culture whose location has yielded only trace human remains.We compare the high-confidence SNPs to those of contemporary populations to find the populations most closely related to the individual. This provides evidence for a migration from Siberia into the New World some 5,500 years ago, independent of that giving rise to the modern Native Americans and Inuit.

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军医

金虫 (初入文坛)

wypward:别着急,请耐心等待! 2010-05-24 21:54:43
wypward:你看到的金币数应该是扣了5个后的数目! 2010-05-24 21:55:24
为什么不给我加金币呀?
3楼2010-05-24 08:31:45
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军医

金虫 (初入文坛)

beidong6938(金币+2, 翻译EPI+1):不够专业。 2010-05-25 11:34:32
我们研究了古代人的基因组序列。从4000年前的冻土层得到的头发分析发现,基因组来自首个格林兰岛定居的男性个体,每隔203测序,覆盖了二倍体基因组的79%,这已经接近了现代测序技术的最大限度。我们鉴定了353151个高通量的单核苷酸多态性。其中6.8%之前没有报道。我们估计漏读的不足0.8%。我们再用功能性单核苷酸多态性分析了这个个体的形态特征并与当代人的多态性比较发现,这个古代人与当代人的多态性数量相近。这位我们提供了5500年前西伯利亚向新大陆迁移的证据,与当今的因纽特人和本地印第安人的产生无关。
2楼2010-05-23 15:25:48
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