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The FICI is defined as the sum of the MIC of each drug when used in combination divided by the drug alone, i.e., FICI (MIC drug A in combination/MIC drug A alone) (MIC drug B in combination/MIC drug B alone). The drug interactions were defined as synergistic if the FICI was <=0.5, indifferent if the FICI was> 0.5 and <=4.0, and antagonistic if the FICI was >4.0. À´Ô´ÓÚANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Aug. 2005, p. 3544¨C3545¡£ |
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