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The standard mode of transmitting manuscripts is for authors to submit them directly to PNAS. Authors must recommend three appropriate Editorial Board members, three NAS members who are expert in the paper's scientific area, and five qualified referees. The Board may choose someone who is or is not on that list or may reject the paper without further review. A directory of PNAS member editors and their research interests is available at http://nrc88.nas.edu/pnas_search. The editor may obtain reviews of the paper from at least two qualified referees, each from a different institution and not from the authors' institutions. For direct submission papers, the PNAS Office will invite the referees, secure the reviews, and forward them to the editor. The PNAS Office will also secure any revisions and subsequent reviews. The name of the editor, who may remain anonymous to the author until the paper is accepted, will be published in PNAS as editor of the article. Papers submitted directly are published as ¡°Edited by¡± the responsible editor and have an additional identifying footnote.

Academy members who have told authors they are willing to oversee the review process have 48 hours from the time of submission to alert the PNAS Office to their request. During this period the PNAS Office will contact the member to confirm. Authors should coordinate submission to ensure the member is available. The Board cannot guarantee that the member designated by the author will be assigned the manuscript or that it will be sent for review. Throughout the review process authors are not permitted to contact the editor directly and all correspondence must be sent through the PNAS office. The standard submission process does not require a prearranged editor. Papers submitted with a prearranged editor are published with a footnote.
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