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帮忙翻译两段英文（晶体）
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Two one-dimensional linear coordination polymers, [Mg(L) _ 4(H2O)] (H2L=olsalazine) and 2[Ca(L) _ 4(H2O)] were obtained from self-assembly of CaCl2 or MgSO4 with olsalazine and their structures determined by single crystal X-ray diffraction. Both complexes are onedimensional polymers, for complex 1 with crystal data: P2(1)/c, a=9.5224(18),b=11.309(2), c=16.211(3)Ǻ , ß=106.648(3)_, V=1672.6(6) Ǻ3, Z=4, R1=0.0695, wR2=0.2183, for complex 2 with crystal data: P4(3)2(1)2, a=10.4006(2), b=10.4006(2), c=32.0746(10) Ǻ , V=3469.59(14) Ǻ3, Z=8, R1=0.0332, wR2=0.1015. In the complexes,Mg and Ca adopt totally different coordination modes. Alkaline-earth Mg is six-coordinate octahedronal geometry, however, in 2, the local coordination geometry around calcium atom can be best described as a slightly distorted pentagonal bipyramid crystallizing in a homo-chiral space group. Olsalazine in both compounds also adopts dissimilar coordination modes. 1. Introduction Studies on the interaction between drugs and metal ions have special applications in medicine [1–4]. Metal complexes can improve the solubility of drugs in water [5] and increase their curative effect; olsalazine sodium can be more effectively absorbed than olsalazine [6]. Studying metal complexes of drugs, aids in understanding the coordination behavior of medicines, useful in pharmacology and in the search for better medicine. Olsalazine (3, 3-azo-bis (6-hydroxybenzoic acid), has been widely used to prevent and treat inflammatory bowel diseases, such as ulcerative colitis [7–9]. Although the sodium, potassium [10], calcium [11] and copper [12] complexes of olsalazine have been reported, other complexes with this molecule have not been reported. In previous work, we have reported a series of Cd, Co and Zn complexes [13] of osalazine with the auxiliary ligand 1,10-phenanthroline. Variation of ligands for bridging and conformational preference as well as the metal ions has a profound influence on the polymeric structures obtained [14]. Herein we report the self-assembly of olsalazine with different alkaline-earth metal salts, which yields two different onedimensional coordination polymers 1 [Mg(L) •4(H2O)] (H2L=olsalazine) and 2 [Ca(L) •4(H2O)], their solid state structures and thermal stabilities.1. Introduction Studies on the interaction between drugs and metal ions have special applications in medicine [1–4]. Metal complexes can improve the solubility of drugs in water [5] and increase their curative effect; olsalazine sodium can be more effectively absorbed than olsalazine [6]. Studying metal complexes of drugs, aids in understanding the coordination behavior of medicines, useful in pharmacology and in the search for better medicine. Olsalazine (3, 3-azo-bis (6-hydroxybenzoic acid), has been widely used to prevent and treat inflammatory bowel diseases, such as ulcerative colitis [7–9]. Although the sodium, potassium [10], calcium [11] and copper [12] complexes of olsalazine have been reported, other complexes with this molecule have not been reported. In previous work, we have reported a series of Cd, Co and Zn complexes [13] of osalazine with the auxiliary ligand 1,10-phenanthroline. Variation of ligands for bridging and conformational preference as well as the metal ions has a profound influence on the polymeric structures obtained [14]. Herein we report the self-assembly of olsalazine with different alkaline-earth metal salts, which yields two different onedimensional coordination polymers 1 [Mg(L) •4(H2O)] (H2L=olsalazine) and 2 [Ca(L) •4(H2O)], their solid state structures and thermal stabilities. 2. Experimental Olsalazine sodium was purchased locally; other chemicals and solvents were purchased from Aldrich and used as received. The FT-IR spectra were recorded as KBr pellets in the range 4000–400 cm-1 on a Nicolet Inpact 170S FT-IR spectrometer. Elemental analysis was performed on Perkin-Elmer 240C elemental analyzer. |
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beata
金虫 (小有名气)
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denjiapin(金币+4):谢谢帮助！ 2010-05-05 13:31:05
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1．前言 药物与金属离子相互作用的研究在医学上有特殊应用[1-4]。金属配合物可提高药物在水中的溶解度[5]，并增加其疗效;奥沙拉嗪钠比奥沙拉嗪[6]更能有效吸收。药物金属配合物的研究，旨在帮助了解药物的协同行为，对药理学和寻找更好的药物非常有用。奥沙拉嗪（3,3 -偶氮二（6 -羟基酸），已被广泛用于预防和治疗炎症性肠道疾病，如溃疡性结肠炎[7-9]。现在已有关于钠，钾[10]，钙[11]和铜[12]奥沙拉嗪配合物的报道，然而这种分子的其他配合物却尚未见报道。在以前的工作中，我们研究了奥沙拉嗪和辅助配体邻菲罗啉的一系列镉，钴，锌配合物 [13]。配体以及金属离子的桥接和构象变化，对获得的高分子结构具有很大的影响 [14]。在此我们通过奥沙拉嗪与不同碱土金属盐自组装，产生了两种不同的一维配位聚合物1和2，并研究其固态结构和热稳定性。 |
3楼2010-05-05 13:09:53
beata
金虫 (小有名气)
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denjiapin(金币+4, 翻译EPI+1):谢谢！ 2010-05-05 13:30:36
| 通过CaCl2 或 MgSO4与偶氮水杨酸自组装，合成了两种一维线性配位聚合物Mg(L) _ 4(H2O)] (H2L=olsalazine) 和 2[Ca(L) _ 4(H2O)]，并用单晶X射线衍射表征其结构。两种复合物都是一维高分子，复合物1晶体数据如下：P2(1)/c, a=9.5224(18),b=11.309(2), c=16.211(3)Ǻ , ß=106.648(3)_, V=1672.6(6) Ǻ3, Z=4, R1=0.0695, wR2=0.2183，复合物2晶体数据如下：P4(3)2(1)2, a=10.4006(2), b=10.4006(2), c=32.0746(10) Ǻ , V=3469.59(14) Ǻ3, Z=8, R1=0.0332, wR2=0.1015.在这两种复合物中，Mg和Ca采用完全不同的配位模式。碱稀土镁是六配位八面体结构，然而，2中，钙原子周围的配位结构可以表述为轻微扭曲的同质手性空间群中的五角双锥晶体。两种化合物中的偶氮水杨酸同样采取不同的配位模式。 |
2楼2010-05-05 12:47:45
beata
金虫 (小有名气)
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4楼2010-05-05 13:13:24
