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求翻译几句医学类英语！先谢谢！
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| Following oral administration, the mean time to peak concentration (Tmax) is 2 to 6 hours.13 Administration of a crushed tablet increased the area under the curve (AUC) by 46% and the peak concentration (Cmax) 2-fold, and decreased the Tmax by 2 hours compared with administration of the whole tablet. Exposure is also increased when pazopanib is administered with food. Administration with a high-fat or low-fat meal resulted in an approximately 2-fold increase in AUC and Cmax. |
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