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王丽84

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[交流] 【讨论】dynamic MRM和MRM的区别

今天听工程师介绍agilent QQQ新出来的扫描方式dynamic MRM,回来找了点资料,还是没有太明白它与MRM相比的优势,说是MRM只是设定几个segment,而dynamic是设置保留时间和变化范围的

文献:

Dynamic MRM methods contrast with conventional MRM methods which rely on user-defined MRM time segments. With DMRM, specific analyte detection may take place over successive MRM timetables depending upon the number of concurrent MRMs and their  respective RT detection windows. Within each DMRM timetable, all ion transitions will have the same dwell time, however, dwell times will vary for each timetable to ensure that all analytes are quantitatively sampled (i.e. provide a sufficient number of data points across all detected peaks). DMRM utilizes a constant cycle time for the DMRM timetables to ensure proper integration of peaks.

请问有人和解释下具体的区别吗,谢谢
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