| 查看: 599 | 回复: 7 | ||
| 当前主题已经存档。 | ||
[交流]
【求助】怎样查找一种进口药品的液相分析方法
|
||
|
怎样查找一种进口药品的液相分析方法 我不是搞药品的，一点头绪也没有，帮帮忙吧！！ |
回复此楼
2楼2010-03-17 19:00:09
catjaja
金虫 (著名写手)
- 应助: 0 (幼儿园)
- 金币: 497.4
- 散金: 49
- 沙发: 1
- 帖子: 1151
- 在线: 23.5小时
- 虫号: 862403
- 注册: 2009-10-03
- 性别: MM
3楼2010-03-17 19:10:18
4楼2010-03-18 08:30:37
5楼2010-03-18 08:31:21
luomuwuhen
金虫 (著名写手)
- 应助: 318 (大学生)
- 金币: 425.8
- 散金: 2134
- 红花: 33
- 帖子: 2539
- 在线: 620.4小时
- 虫号: 770047
- 注册: 2009-05-14
- 性别: GG
- 专业: 有机合成
6楼2010-03-18 08:43:43
7楼2010-03-18 09:52:44
luomuwuhen
金虫 (著名写手)
- 应助: 318 (大学生)
- 金币: 425.8
- 散金: 2134
- 红花: 33
- 帖子: 2539
- 在线: 620.4小时
- 虫号: 770047
- 注册: 2009-05-14
- 性别: GG
- 专业: 有机合成
bending(金币+30):万分感谢，好人啊！！ 2010-03-18 10:17
|
Google上搜索的摘要，有用 The reversed-phase high-performance liquid chromatographic (RP-HPLC) method has been developed and validated for the simultaneous determination of imatinib mesylate and of the impurity product in Glivec capsules (Novartis, Switzerland). Separations were performed on a X Terra 150 mm x 4.6 mm, 5 microm particle size column at 25 degrees C. The mobile phase was a mixture of methanol-water-triethylamine (25:74:1, v/v/v) with flow rate of 1.0 ml min(-1). pH value of water-triethylamine (TEA) was adjusted to 2.4 with orthophosphoric acid before adding of methanol. UV detection was performed at 267 nm. Acetaminophen was used as an internal standard. The method was validated statistically for its selectivity, linearity, precision, accuracy and robustness. Due to its speed and accuracy, the method may be used for quality control analyses. 柱温25度 流动相：甲醇-水-三乙胺（25：74：1），水和三乙胺用磷酸调节PH2.4，然后加入甲醇。 流速1.0ml/min 检测波长267nm [ Last edited by luomuwuhen on 2010-3-18 at 10:04 ] |
8楼2010-03-18 09:57:03