| 查看: 162 | 回复: 1 | |||
| 当前主题已经存档。 | |||
rena6816至尊木虫 (著名写手)
|
[交流]
【推荐】A Comparison of the Effects of Three GM Corn Varieties on Mammalian Heal
|
||
|
A Comparison of the Effects of Three GM Corn Varieties on Mammalian Health Joel Spiroux de Vendomois, François Roullier, Dominique Cellier, Gilles-Eric Seralini. Int J Biol Sci 2009; 5:706-726. Received: 2009.07.23; Accepted: 2009.11.17; Published: 2009.12.10 Abstract We present for the first time a comparative analysis of blood and organ system data from trials with rats fed three main commercialized genetically modified (GM) maize (NK 603, MON 810, MON 863), which are present in food and feed in the world. NK 603 has been modified to be tolerant to the broad spectrum herbicide Roundup and thus contains residues of this formulation. MON 810 and MON 863 are engineered to synthesize two different Bt toxins used as insecticides. Approximately 60 different biochemical parameters were classified per organ and measured in serum and urine after 5 and 14 weeks of feeding. GM maize-fed rats were compared first to their respective isogenic or parental non-GM equivalent control groups. This was followed by comparison to six reference groups, which had consumed various other non-GM maize varieties. We applied nonparametric methods, including multiple pairwise comparisons with a False Discovery Rate approach. Principal Component Analysis allowed the investigation of scattering of different factors (sex, weeks of feeding, diet, dose and group). Our analysis clearly reveals for the 3 GMOs new side effects linked with GM maize consumption, which were sex- and often dose-dependent. Effects were mostly associated with the kidney and liver, the dietary detoxifying organs, although different between the 3 GMOs. Other effects were also noticed in the heart, adrenal glands, spleen and haematopoietic system. We conclude that these data highlight signs of hepatorenal toxicity, possibly due to the new pesticides specific to each GM corn. In addition, unintended direct or indirect metabolic consequences of the genetic modification cannot be excluded. Keywords: GMO, toxicity, GM corn, rat, NK 603, MON 810, MON 863 http://www.namipan.com/d/A%20Com ... alian%20Health.PDF/ |
回复此楼» 猜你喜欢
面上可以超过30页吧？
已经有6人回复
-
体制内长辈说体制内绝大部分一辈子在底层，如同你们一样大部分普通教师忙且收入低
已经有14人回复
-
网上报道青年教师午睡中猝死、熬夜猝死的越来越多，主要哪些原因引起的？
已经有4人回复
-
为什么中国大学工科教授们水了那么多所谓的顶会顶刊，但还是做不出宇树机器人？
已经有10人回复
-
版面费该交吗
已经有12人回复
-
“人文社科而论，许多学术研究还没有达到民国时期的水平”
已经有5人回复
-
什么是人一生最重要的？
已经有4人回复
★ ★ ★
小木虫(金币+0.5):给个红包，谢谢回帖交流
amisking(金币+2): 2010-03-07 18:57
小木虫(金币+0.5):给个红包，谢谢回帖交流
amisking(金币+2): 2010-03-07 18:57
| 试试这个链接http://www.biolsci.org/v05p0706.htm ！文章的结论：In conclusion, our data presented here strongly recommend that additional long-term (up to 2 years) animal feeding studies be performed in at least three species, preferably also multi-generational, to provide true scientifically valid data on the acute and chronic toxic effects of GM crops, feed and foods. Our analysis highlights that the kidneys and liver as particularly important on which to focus such research as there was a clear negative impact on the function of these organs in rats consuming GM maize varieties for just 90 days. |
2楼2010-03-07 18:03:57