| 查看: 193 | 回复: 1 | |||
| 当前主题已经存档。 | |||
rena6816至尊木虫 (著名写手)
|
[交流]
【推荐】A Comparison of the Effects of Three GM Corn Varieties on Mammalian Heal
|
||
|
A Comparison of the Effects of Three GM Corn Varieties on Mammalian Health Joel Spiroux de Vendomois, François Roullier, Dominique Cellier, Gilles-Eric Seralini. Int J Biol Sci 2009; 5:706-726. Received: 2009.07.23; Accepted: 2009.11.17; Published: 2009.12.10 Abstract We present for the first time a comparative analysis of blood and organ system data from trials with rats fed three main commercialized genetically modified (GM) maize (NK 603, MON 810, MON 863), which are present in food and feed in the world. NK 603 has been modified to be tolerant to the broad spectrum herbicide Roundup and thus contains residues of this formulation. MON 810 and MON 863 are engineered to synthesize two different Bt toxins used as insecticides. Approximately 60 different biochemical parameters were classified per organ and measured in serum and urine after 5 and 14 weeks of feeding. GM maize-fed rats were compared first to their respective isogenic or parental non-GM equivalent control groups. This was followed by comparison to six reference groups, which had consumed various other non-GM maize varieties. We applied nonparametric methods, including multiple pairwise comparisons with a False Discovery Rate approach. Principal Component Analysis allowed the investigation of scattering of different factors (sex, weeks of feeding, diet, dose and group). Our analysis clearly reveals for the 3 GMOs new side effects linked with GM maize consumption, which were sex- and often dose-dependent. Effects were mostly associated with the kidney and liver, the dietary detoxifying organs, although different between the 3 GMOs. Other effects were also noticed in the heart, adrenal glands, spleen and haematopoietic system. We conclude that these data highlight signs of hepatorenal toxicity, possibly due to the new pesticides specific to each GM corn. In addition, unintended direct or indirect metabolic consequences of the genetic modification cannot be excluded. Keywords: GMO, toxicity, GM corn, rat, NK 603, MON 810, MON 863 http://www.namipan.com/d/A%20Com ... alian%20Health.PDF/ |
回复此楼» 猜你喜欢
澳大利亚 Murdoch University 全奖博士招生（3个名额）地质化工冶金领域
已经有16人回复
-
FileCode能看出啥？
已经有27人回复
-
欢迎发来filecode的Mz6后的代码验证其规律
已经有12人回复
-
静等基金结果
已经有19人回复
-
阿姨
已经有3人回复
-
有时候，自然基金真的不能太认真 （我的申报经验）
已经有6人回复
-
filecode
已经有16人回复
-
重要来源：本周末出结果
已经有10人回复
-
咱们一起用铁证分析2026国家社科基金中标与否
已经有6人回复
-
不应该看fileCode
已经有9人回复
★ ★ ★
小木虫(金币+0.5):给个红包，谢谢回帖交流
amisking(金币+2): 2010-03-07 18:57
小木虫(金币+0.5):给个红包，谢谢回帖交流
amisking(金币+2): 2010-03-07 18:57
| 试试这个链接http://www.biolsci.org/v05p0706.htm ！文章的结论：In conclusion, our data presented here strongly recommend that additional long-term (up to 2 years) animal feeding studies be performed in at least three species, preferably also multi-generational, to provide true scientifically valid data on the acute and chronic toxic effects of GM crops, feed and foods. Our analysis highlights that the kidneys and liver as particularly important on which to focus such research as there was a clear negative impact on the function of these organs in rats consuming GM maize varieties for just 90 days. |
2楼2010-03-07 18:03:57
