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ϸ°ûÉ«ËØP450 (Cytochrome P450)ÊDzÎÓëÀ¥³æÌåÄÚ¸÷ÖÖɱ³æ¼ÁÒÔ¼°ÆäËüÍâÔ´ÐÔºÍÄÚÔ´ÐÔ»¯ºÏÎï´úлµÄÖ÷Òª½â¶¾Ã¸Ïµ£¬ÊÇ΢Á£Ìå¶à¹¦ÄÜÑõ»¯Ã¸£¨MFO£©µÄÄ©¶ËÑõ»¯Ã¸, ÓÐ×ÅÓëµ×Îï½áºÏÒÔ¼°´ÓNADPH ´«µÝµç×Óµ½NADPH ϸ°ûÉ«ËØP450»¹ÔøµÄÖØÒª¹¦ÄÜ Cytochrome P450 (Cytochrome P450) are involved in a variety of insecticides in insects and other exogenous and endogenous compounds, the major detoxification enzymes in metabolism is the microsomal mixed-function oxidase (MFO) of the terminal oxidase, with and substrate binding as well as from the transmission of electronic NADPH to NADPH cytochrome P450 reductase, an important function ÒòÆäÖ÷Òª³É·Ö P450µ°°×Óë CO µÄ½áºÏÌåÔÚOD 450 nm´¦ÓÐÌØÕ÷¹âÎüÊÕ·å¶øµÃÃû¡£ Cytochrome P450øϵ²ÎÓëÀ¥³æÉú³¤¡¢·¢Óý¡¢È¡Ê³µÈÉúÀíÉú»¯¹ý³Ì,Ö¸µ¼À¥³æ¶Ôɱ³æ¼Á²úÉú¿¹Ò©ÐԺͶÔÖ²ÎïÓж¾ÎïÖÊÄÍÊÜÐÔ,°üÀ¨¶ÔÖ²Îï´ÎÉúÎïÖÊ´úлºÍɱ³æ¼Á½â¶¾µÈ,ÓÐÀûÓÚÀ¥³æÊÊÓ¦²»¶Ï±ä»¯µÄ»·¾³£»ÒòÆäÉúÎïѧµÄÖØÒªÐÔ,¸ÃøһֱÊÇÉúÎïѧÑо¿µÄÒ»¸öÈȵã P450 protein and its major components a combination of CO in the OD 450 nm light at a characteristic absorption peak is named. Cytochrome P450 enzymes involved in insect growth, development, feeding and other physiological and biochemical processes, guiding insects resistant to pesticides and toxic substances tolerance of plants, including plant secondary metabolism and detoxification of pesticides and so on, there are beneficial insects to adapt to the changing environment; its biological importance, the enzyme has been a hot biological research 1967Äê, RayÊ״ᨵÀÀ¥³æÖдæÔÚϸ°ûÉ«ËØP450»ùÒò,Ëæ¼´ÒýÆðÁËÐí¶àÑо¿Õߵļ«´óÐËȤ¡£ÓÉÓÚÀ¥³æÌåÄÚµÄϸ°ûÉ«ËØP450º¬Á¿Æ«µÍ¡¢ÖÖÀà·±¶àÇÒ²»Îȶ¨£¬ÄÑÓÚ·ÖÀë³öµ¥Ò»ÐÍϸ°ûÉ«ËØP450µÈÔÒò£¬ÓÃÒ»°ãµÄøѧºÍÉú»¯·½·¨¶ÔÀ¥³æµ¥Ò»Ð͵Äϸ°ûÉ«ËØP450ÌØÐÔ½øÐÐÉîÈëϸÖµÄÑо¿´ï²»µ½ÀíÏëЧ¹û¡£×Ô´ÓFeyereisenµÈ(1989)´Ó¼ÒÓ¬(Musca domestica )ÌåÄÚ·ÖÀë³öµÚÒ»¸öÀ¥³æÏ¸°ûÉ«ËØP450»ùÒò,ÓÉ´Ë±ã½øÈëÁË´Ó·Ö×ÓˮƽÉ϶ÔÀ¥³æµ¥Ò»ÐÍϸ°ûÉ«ËØP450µÄÑо¿ ¡£ In 1967, Ray was first reported the existence of insect cytochrome P450 genes, which immediately caused great interest of many researchers. As the insect cytochrome P450 content of the low side, a wide variety and unstable, difficult to isolate a single type of cytochrome P450 and other reasons, to use normal enzymatic and biochemical methods on a single type of insect cytochrome P450 features an in-depth and detailed study of not reach the desired result . Since the Feyereisen et al (1989) from the housefly (Musca domestica) in vivo isolated the first insect cytochrome P450 genes, this will enter the molecular level from a single type of insect cytochrome P450 studies . |
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xiaoqihu
Ìú¸Ëľ³æ (ÖøÃûдÊÖ)
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2Â¥2010-03-05 10:41:44
xiaoqihu
Ìú¸Ëľ³æ (ÖøÃûдÊÖ)
- ·ÒëEPI: 88
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- ¹ó±ö: 0.005
- ½ð±Ò: 9724.8
- É¢½ð: 7
- ºì»¨: 4
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- ³æºÅ: 590066
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3Â¥2010-03-05 10:42:22
liuqiuning
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4Â¥2010-03-05 10:42:57
liuqiuning
ľ³æ (ÕýʽдÊÖ)
- Ó¦Öú: 12 (СѧÉú)
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- Ìû×Ó: 765
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- ×¢²á: 2008-11-26
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5Â¥2010-03-05 11:07:16














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