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Reviewers' comments:


Reviewer #1: The authors decribe ********. A very similar work has been published by Augustijns where increased absortion of **********.
The authors should explain why they have selected ****among many possible esters for this study. In my opinion much impressive study could be obtained when ***** are included and compared.



Reviewer #2: The manuscript for "Absorption enhancement of Adefovir Dipivoxil by incorporating esterase inhibitor ethyl oleate in emulsion as part of oil excipient"
is extremely well designed. Authors discussed their results with most recent literature and cited most updated literature. Inserted tables and figures are high quality.
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     I apologize for the later reply to your mail dated 21th February regarding the rejection of your manuscript. As already mentioned in my first mail EJPS gets a significant number of manuscript and many more of good scientific quality than can be published. So as editors we are under a certain pressure and often have to reject manuscript we would have been pleased to publish if the journal had more volumes available. My rejection was as you could see based on the comments primarily by reviewer 1 who asked questions on novelty. However, I have been carefully through your manuscript again and from a general point of view I still agree with the reviewer. However, I would be prepare to look at the manuscript ¨C but as a new submission ¨C if are able to revise the manuscript and clearly work and discuss the novelty compared the e.g. prof. Augustijns¡¯s work e.g. more focus on functional excipients and lipid formulation.
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